Workbook for Organic Synthesis

Strategy and Control
Author: Paul Wyatt,Stuart Warren
Publisher: Wiley
ISBN: 9780471929642
Category: Science
Page: 502
View: 1271

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This workbook accompanies Organic Synthesis: Strategy and Control, the bestselling advanced organic textbook Provides a complete course for advanced organic students and includes a graded set of problems, solutions and discussions to illustrate and develop the themes of each of the chapters in the textbook

Workbook for Organic Synthesis: The Disconnection Approach


Author: Stuart Warren,Paul Wyatt
Publisher: John Wiley & Sons
ISBN: 1119965551
Category: Science
Page: 272
View: 5467

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One approach to organic synthesis is retrosynthetic analysis. With this approach chemists start with the structures of their target molecules and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Workbook for Organic Synthesis: The Disconnection Approach, 2nd Edition This workbook provides a comprehensive graded set of problems to illustrate and develop the themes of each of the chapters in the textbook Organic Synthesis: The Disconnection Approach, 2nd Edition. Each problem is followed by a fully explained solution and discussion. The examples extend the student’s experience of the types of molecules being synthesised by organic chemists, and the strategies they employ to control their syntheses. By working through these examples students will develop their skills in analysing synthetic challenges, and build a toolkit of strategies for planning new syntheses. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. Together the workbook and textbook provide a complete course in retrosynthetic analysis. Organic Synthesis: The Disconnection Approach, 2nd Edition There are forty chapters in Organic Synthesis: The Disconnection Approach, 2nd Edition: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. In its second edition updated examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, Organic Synthesis: Strategy and Control. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Workbook for Organic Synthesis: The Disconnection Approach, 2nd edition, combined with the main textbook, provides a full course in retrosynthetic analysis for chemistry and biochemistry students, and a refresher course for organic chemists working in industry and academia.

Organische Chemie


Author: Jonathan Clayden,Nick Greeves,Stuart Warren
Publisher: Springer Spektrum
ISBN: 9783642347153
Category: Science
Page: 1366
View: 4511

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Ein neuer Stern am Lehrbuch-Himmel: Organische Chemie von Clayden, Greeves, Warren - der ideale Begleiter für alle Chemiestudenten. Der Schwerpunkt dieses didaktisch durchdachten, umfassenden vierfarbigen Lehrbuches liegt auf dem Verständnis von Mechanismen, Strukturen und Prozessen, nicht auf dem Lernen von Fakten. Organische Chemie entpuppt sich als dabei als ein kohärentes Ganzes, mit zahlreichen logischen Verbindungen und Konsequenzen sowie einer grundlegenden Struktur und Sprache. Dank der Betonung von Reaktionsmechanismen, Orbitalen und Stereochemie gewinnen die Studierenden ein solides Verständnis der wichtigsten Faktoren, die für alle organisch-chemischen Reaktionen gelten. So lernen sie, auch Reaktionen, die ihnen bisher unbekannt waren, zu interpretieren und ihren Ablauf vorherzusagen. Der direkte, persönliche, studentenfreundliche Schreibstil motiviert die Leser, mehr erfahren zu wollen. Umfangreiche Online-Materialien führen das Lernen über das gedruckte Buch hinaus und vertiefen das Verständnis noch weiter.

Organic Synthesis, Workbook

The Disconnection Approach
Author: Stuart Warren
Publisher: John Wiley & Sons
ISBN: 9780471900825
Category: Science
Page: 540
View: 5242

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A workbook providing additional examples, problems, and solutions for use with Warren′s Organic Synthesis: The Disconnection Approach. Exercises correspond to chapters in the main text. Problems of special ease or difficulty are labeled for optional use. Workbook includes a formula index of all target molecules contained in the text and workbook.

Organische Chemie für Dummies


Author: Arthur Winter
Publisher: John Wiley & Sons
ISBN: 3527822402
Category: Science
Page: 370
View: 2852

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Man könnte meinen, dass eine Wissenschaft, die sich hauptsächlich mit Verbindungen eines einzigen Elements auseinandersetzt, vergleichsweise übersichtlich ist. Doch Kohlenstoff ist ein ganz besonderes Element, denn Kohlenstoffverbindungen bilden die Grundlagen des Lebens. "Organische Chemie für Dummies" führt Sie in die Geheimnisse der organischen Verbindungen ein, erklärt Ihnen die Grundlagen der Spektrometrie und Spektroskopie, zeigt Ihnen, welche Reaktionen möglich und welche unmöglich sind und vieles mehr. Nach jedem Kapitel finden Sie Übungsaufgaben mit ausführlichen Lösungen. So unterstützt Sie das Buch bei Ihrem Einstieg in die Organische Chemie.

Biochemie für Dummies


Author: John W. Moore
Publisher: John Wiley & Sons
ISBN: 3527657959
Category: Science
Page: 330
View: 692

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Im Leben eines Biologen und auch in dem eines Chemikers kommt irgendwann der Tag, an dem plötzlich die Biochemie vor der Tür steht oder gleich hineinpoltert. "Biochemie für Dummies" bereitet Sie auf diesen Tag vor oder hilft Ihnen, die Folgen zu verkraften. Von Zellstrukturen über Kohlenwasserstoffe, Aminosäuren und Proteine erklärt Ihnen das was Sie über Biochemie wissen müssen. So einfach wie möglich, so komplex wie nötig werden Sie hier in die Welt der Lipide, Vitamine und Hormone eingeführt und erfahren, was ATP jenseits des Tennisplatzes bedeutet.

Factfulness

Wie wir lernen, die Welt so zu sehen, wie sie wirklich ist
Author: Hans Rosling,Anna Rosling Rönnlund,Ola Rosling
Publisher: Ullstein Buchverlage
ISBN: 3843717451
Category: Science
Page: 350
View: 2394

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Es wird alles immer schlimmer, eine schreckliche Nachricht jagt die andere: Die Reichen werden reicher, die Armen ärmer. Es gibt immer mehr Kriege, Gewaltverbrechen, Naturkatastrophen. Viele Menschen tragen solche beängstigenden Bilder im Kopf. Doch sie liegen damit grundfalsch. Unser Gehirn verführt uns zu einer dramatisierenden Weltsicht, die mitnichten der Realität entspricht, wie der geniale Statistiker und Wissenschaftler Hans Rosling erklärt. Wer das Buch gelesen hat, wird • ein sicheres, auf Fakten basierendes Gerüst besitzen, um die Welt so zu sehen, wie sie wirklich ist • die zehn gängigsten Arten von aufgebauschten Geschichten erkennen • bessere Entscheidungen treffen können • wahre Factfulness erreichen – jene offene, neugierige und entspannte Geisteshaltung, in der Sie nur noch Ansichten teilen und Urteile fällen, die auf soliden Fakten basieren

Gefängnis-Hefte

Hefte 16 bis 21 / hrsg. von Klaus Bochmann ... Unter Mitw. von Ruedi Graf und Gerhard Kuck
Author: Antonio Gramsci
Publisher: N.A
ISBN: 9783867541008
Category:
Page: 269
View: 8386

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Organic Synthesis

The Disconnection Approach
Author: Stuart Warren,Paul Wyatt
Publisher: John Wiley & Sons
ISBN: 1119965535
Category: Science
Page: 342
View: 6459

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One approach to organic synthesis is retrosynthetic analysis. With this approach a chemist will start with the structure of their target molecule and progressively cut bonds to create simpler molecules. Reversing this process gives a synthetic route to the target molecule from simpler starting materials. This “disconnection” approach to synthesis is now a fundamental part of every organic synthesis course. Organic Synthesis: The Disconnection Approach, 2nd Edition introduces this important technique, to help students to design their own organic syntheses. There are forty chapters: those on the synthesis of given types of molecules alternate with strategy chapters in which the methods just learnt are placed in a wider context. The synthesis chapters cover many ways of making each type of molecule starting with simple aromatic and aliphatic compounds with one functional group and progressing to molecules with many functional groups. The strategy chapters cover questions of selectivity, protection, stereochemistry, and develop more advanced thinking via reagents specifically designed for difficult problems. Examples are drawn from pharmaceuticals, agrochemicals, natural products, pheromones, perfumery and flavouring compounds, dyestuffs, monomers, and intermediates used in more advanced synthetic work. Reasons for wishing to synthesise each compound are given. This second edition has been fully revised and updated with a modern look. Recent examples and techniques are included and illustrated additional material has been added to take the student to the level required by the sequel, “Organic Synthesis: Strategy and Control”. Several chapters contain extensive new material based on courses that the authors give to chemists in the pharmaceutical industry. Organic Synthesis: The Disconnection Approach, 2nd edition provides a full course in retrosynthetic analysis for chemistry and biochemistry students and a refresher for organic chemists working in industry and academia.

Molekülorbitale und Reaktionen organischer Verbindungen


Author: Ian Fleming
Publisher: John Wiley & Sons
ISBN: 3527330690
Category: Chemical bonds
Page: 399
View: 3915

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Der lang erwartete Nachfolger des Klassikers "Grenzorbitale und Reaktionen organischer Verbindungen". Die Molekülorbitalheorie wird einfach, ohne komplizierte mathematische Formeln und mit vielen illustrativen Beispielen erklärt.

Elektronen und Chemische Bindung


Author: Harry B. Gray
Publisher: Walter de Gruyter
ISBN: 3110830620
Category: Reference
Page: 205
View: 8014

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“Electrons and chemical bonding: This standard textbook on quantum chemistry is easy to understand even for chemists; its basic concepts never become obsolete. Well done didactically, concise and to-the-point.” Prof. Dr. Ralf Steudel, TU Berlin

Formulierungstechnik

Emulsionen, Suspensionen, Feste Formen
Author: Hans Mollet,Arnold Grubenmann
Publisher: John Wiley & Sons
ISBN: 3527625712
Category: Science
Page: 453
View: 540

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Viele chemische Stoffe und Verbindungen werden nicht in reiner Form angewandt. Um die beste Entfaltung des Wirkstoffes zu ermöglichen oder die optimalen Handels- oder Verkaufsform zu erreichen, schließen sich an die Synthese und Reinigung die Aufbereitung und Formulierung an. Die Palette der Handelsformen reicht von Pulvern, Agglomeraten, Granulaten, Suspensionen, Slurries, Emulsionen, Mikroemulsionen, Mikrokapseln, Instantpräparaten, Liposomen bis hin zu Tabletten und Dragees. Die Formulierung kann je nach Präparat in einer einfachen Mischoperation bestehen oder kompliziertere verfahrenstechnische Schritte, wie Zerkleinern, Dispergieren, Emulgieren, Agglomerieren, Solubilisieren, Trocknen usw. einschließen. Sie spannt den Bogen von der Kolloid- und Grenzflächenchemie zur Verfahrenstechnik. In diesem Buch werden die für den Formulierungschemiker in der Industrie wesentlichen physikalisch-chemischen Grundlagen und Anwendungen in der chemischen Industrie, z.B. für Pharmazeutika, Agrochemikalien, Pigmente, Farbstoffe, Lebensmittel, Additive, Waschmittel und Kosmetika sowie die geeigneten Hilfsmittel für die Struktur-Wirkungsbeziehung übersichtlich und praxisnah beschrieben.

BEST WEIGHT

Ein Leitfaden für das Adipositas-Management in der Praxis
Author: Yoni Freedhoff,Arya M. Sharma
Publisher: N.A
ISBN: 9783899678338
Category: Weight loss
Page: 147
View: 7163

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Elemente der Syntheseplanung


Author: R.W. Hoffmann
Publisher: Spektrum Akademischer Verlag
ISBN: 9783827417251
Category: Science
Page: 206
View: 7497

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Bei der Syntheseplanung ist es wie beim Gebrauchtwagenkauf: Man kann folgenschwere Fehler machen, und jeder Fall ist anders! Und dennoch gibt es Tipps, woran man denken sollte und was man beachten muss! Dieses Buch führt in die elementaren Überlegungen ein, die man bei der Planung einer Synthese anstellen sollte. Diese Überlegungen illustriert R.W. Hoffmann mit zahlreichen Beispielen aus publizierten Synthesen. Bei jedem Beispiel gibt er die Originalliteraturstelle an, bei der Interessierte Details und weitere Erklärungen nachlesen können.

Organic Synthesis


Author: Michael B Smith
Publisher: Academic Press
ISBN: 0128008075
Category: Science
Page: 1106
View: 4694

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Organic Synthesis, Fourth Edition, provides a reaction-based approach to this important branch of organic chemistry. Updated and accessible, this eagerly-awaited revision offers a comprehensive foundation for graduate students coming from disparate backgrounds and knowledge levels, to provide them with critical working knowledge of basic reactions, stereochemistry and conformational principles. This reliable resource uniquely incorporates molecular modeling content, problems, and visualizations, and includes reaction examples and homework problems drawn from the latest in the current literature. In the Fourth Edition, the organization of the book has been improved to better serve students and professors and accommodate important updates in the field. The first chapter reviews basic retrosynthesis, conformations and stereochemistry. The next three chapters provide an introduction to and a review of functional group exchange reactions; these are followed by chapters reviewing protecting groups, oxidation and reduction reactions and reagents, hydroboration, selectivity in reactions. A separate chapter discusses strategies of organic synthesis, and he book then delves deeper in teaching the reactions required to actually complete a synthesis. Carbon-carbon bond formation reactions using both nucleophilic carbon reactions are presented, and then electrophilic carbon reactions, followed by pericyclic reactions and radical and carbene reactions. The important organometallic reactions have been consolidated into a single chapter. Finally, the chapter on combinatorial chemistry has been removed from the strategies chapter and placed in a separate chapter, along with valuable and forward-looking content on green organic chemistry, process chemistry and continuous flow chemistry. Throughout the text, Organic Synthesis, Fourth Edition utilizes Spartan-generated molecular models, class tested content, and useful pedagogical features to aid student study and retention, including Chapter Review Questions, and Homework Problems. PowerPoint© presentations and answer keys are also available online to support instructors. Fully revised and updated throughout, and teorganized into 19 chapters for a more cogent and versatile presentation of concepts Includes reaction examples taken from literature research reported between 2010-2015 Features new full-color art and new chapter content on process chemistry and green organic chemistry Offers valuable study and teaching tools, including Chapter Review Questions and Homework Problems for students; Lecture presentations and other useful material for qualified course instructors

Der Sklavenaufstand von Haiti

ethnische Differenz und Humanitätsideale in der Literatur des 19. Jahrhunderts
Author: Marie Biloa Onana
Publisher: Böhlau Verlag Köln Weimar
ISBN: 9783412204532
Category: French literature
Page: 217
View: 1156

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Organic Synthesis


Author: Michael Smith
Publisher: Academic Press
ISBN: 1890661406
Category: Science
Page: 1506
View: 1294

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A reactions oriented course is a staple of most graduate organic programs, and synthesis is taught either as a part of that course or as a special topic. Ideally, the incoming student is an organic major, who has a good working knowledge of basic reactions, stereochemistry and conformational principles. In fact, however, many (often most) of the students in a first year graduate level organic course have deficiencies in their undergraduate work, are not organic majors and are not synthetically inclined. To save students much time catching up this text provides a reliable and readily available source for background material that will enable all graduate students to reach the same high level of proficiency in organic chemistry. Produced over many years with extensive feedback from students taking an organic chemistry course this book provides a reaction based approach. The first two chapters provide an introduction to functional groups; these are followed by chapters reviewing basic organic transformations (e.g. oxidation, reduction). The book then looks at carbon-carbon bond formation reactions and ways to 'disconnect' a bigger molecule into simpler building blocks. Most chapters include an extensive list of questions to test the reader's understanding. There is also a new chapter outlining full retrosynthetic analyses of complex molecules which highlights common problems made by scientists. The book is intended for graduate and postgraduate students, scientific researchers in chemistry New publisher, new edition; extensively updated and corrected Over 950 new references with more than 6100 references in total Over 600 new reactions and figures replaced or updated Over 300 new homework problems from the current literature to provide nearly 800 problems to test reader understanding of the key principles Free molecular modeling software to explore 60 new synthesis-oriented molecular modeling problems; designed to aid visualisation and understanding of organic synthesis