The Making of a Fly

The Genetics of Animal Design
Author: P. A. Lawrence
Publisher: Wiley-Blackwell
ISBN: 9780632030484
Category: Science
Page: 240
View: 1229

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Understanding how a multicellular animal develops from a single cell (the fertilized egg) poses one of the greatest challenges in biology today. Development from egg to adult involves the sequential expression of virtually the whole of an organism's genetic instructions both in the mother as she lays down developmental cues in the egg, and in the embryo itself. Most of our present information on the role of genes in development comes from the invertebrate fruit fly, Drosophila. The two authors of this text (amongst the foremost authorities in the world) follow the developmental process from fertilization through the primitive structural development of the body plan of the fly after cleavage into the differentiation of the variety of tissues, organs and body parts that together define the fly. The developmental processes are fully explained throughout the text in the modern language of molecular biology and genetics. This text represents the vital synthesis of the subject that many have been waiting for and it will enable many specific courses in developmental biology and molecular genetics to focus on it. It will appeali to 2nd and 3rd year students in these disciplines as well as in biochemistry, neurobiology and zoology. It will also have widespread appeal among researchers. Authored by one of the foremost authorities in the world. A unique synthesis of the developmental cycle of Drosophila - our major source of information on the role of genes in development. Designed to provide the basis of new courses in developmental biology and molecular genetics at senior undergraduate level. A lucid explanation in the modern language of the science.

The Evolutionary Biology of Flies


Author: David K. Yeates,Brian M. Wiegmann
Publisher: Columbia University Press
ISBN: 0231127006
Category: Science
Page: 430
View: 3740

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Classical Japanese: A Grammar is a comprehensive, and practical guide to classical Japanese. Extensive notes and historical explanations make this volume useful as both a reference for advanced students and a textbook for beginning students. The volume, which explains how classical Japanese is related to modern Japanese, includes detailed explanations of basic grammar, including helpful, easy-to-use tables of grammatical forms; annotated excerpts from classical premodern texts. Classical Japanese: A Grammar - Exercise Answers and Tables (ISBN: 978-0-231-13530-6) is now available for purchase as a separate volume.

Das egoistische Gen

Mit einem Vorwort von Wolfgang Wickler
Author: Richard Dawkins
Publisher: Springer-Verlag
ISBN: 3642553915
Category: Science
Page: 489
View: 1729

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p”Ein auch heute noch bedeutsamer Klassiker“ Daily Express Sind wir Marionetten unserer Gene? Nach Richard Dawkins ́ vor über 30 Jahren entworfener und heute noch immer provozierender These steuern und dirigieren unsere von Generation zu Generation weitergegebenen Gene uns, um sich selbst zu erhalten. Alle biologischen Organismen dienen somit vor allem dem Überleben und der Unsterblichkeit der Erbanlagen und sind letztlich nur die "Einweg-Behälter" der "egoistischen" Gene. Sind wir Menschen also unserem Gen-Schicksal hilflos ausgeliefert? Dawkins bestreitet dies und macht uns Hoffnung: Seiner Meinung nach sind wir nämlich die einzige Spezies mit der Chance, gegen ihr genetisches Schicksal anzukämpfen.

Molekulare Zellbiologie


Author: Arnold Berk,David Baltimore,Harvey Lodish,James Darnell,Paul Matsudaira,S. Lawrence Zipursky
Publisher: Walter de Gruyter
ISBN: 3110810573
Category: Science
Page: 1491
View: 9199

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Insect Molecular Genetics

An Introduction to Principles and Applications
Author: Marjorie A. Hoy
Publisher: Academic Press
ISBN: 0240821319
Category: Science
Page: 838
View: 4508

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Insect Molecular Genetics, Third Edition, summarizes and synthesizes two rather disparate disciplines—entomology and molecular genetics. This volume provides an introduction to the techniques and literature of molecular genetics; defines terminology; and reviews concepts, principles, and applications of these powerful tools. The world of insect molecular genetics, once dominated by Drosophila, has become much more diverse, especially with the sequencing of multiple arthropod genomes (from spider mites to mosquitoes). This introduction includes discussion of honey bees, mosquitoes, flour beetles, silk moths, fruit flies, aphids, house flies, kissing bugs, cicadas, butterflies, tsetse flies and armyworms. This book serves as both a foundational text and a review of a rapidly growing literature. With fully revised and updated chapters, the third edition will be a valuable addition to the personal libraries of entomologists, geneticists, and molecular biologists. Up-to-date references to important review articles, websites, and seminal citations in the disciplines Well crafted and instructive illustrations integral to explaining the techniques of molecular genetics Glossary of terms to help beginners learn the vocabulary of molecular biology

Das Wunder der wilden Insel


Author: Peter Brown
Publisher: cbt Verlag
ISBN: 3641194466
Category: Juvenile Fiction
Page: 288
View: 9798

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Preisgekrönt und bezaubernd: ein moderner Klassiker Als das Robotermädchen Roz erstmals die Augen öffnet, findet sie sich auf einer wilden, einsamen Insel wieder. Wie sie dorthin gekommen ist und warum, weiß sie nicht. Das Wetter und ein wilder Bär setzen ihr übel zu, und Roz begreift, dass sie sich ihrer Umgebung anpassen muss, wenn sie überleben will. Also beobachtet sie, erlernt die Sprache der Tiere und entdeckt, dass Freundlichkeit und Hilfsbereitschaft sie weiterbringen. Viele würden das Blechmonster zwar am liebsten verjagen, aber Roz gibt nicht auf. Sie zieht ein Gänseküken auf, und endlich fassen die Tiere Vertrauen. Als Roz dann in großer Gefahr schwebt, stehen sie ihr als Freunde bei.

Philosophy of Experimental Biology


Author: Marcel Weber
Publisher: Cambridge University Press
ISBN: 9781139453912
Category: Science
Page: N.A
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Philosophy of Experimental Biology explores some central philosophical issues concerning scientific research in experimental biology, including genetics, biochemistry, molecular biology, developmental biology, neurobiology, and microbiology. It seeks to make sense of the explanatory strategies, concepts, ways of reasoning, approaches to discovery and problem solving, tools, models and experimental systems deployed by scientific life science researchers and also integrates developments in historical scholarship, in particular the New Experimentalism. It concludes that historical explanations of scientific change that are based on local laboratory practice need to be supplemented with an account of the epistemic norms and standards that are operative in science. This book should be of interest to philosophers and historians of science as well as to scientists.

Towards a Theory of Development


Author: Alessandro Minelli,Thomas Pradeu
Publisher: OUP Oxford
ISBN: 0191651184
Category: Science
Page: 320
View: 9313

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Is it possible to explain and predict the development of living things? What is development? Articulate answers to these seemingly innocuous questions are far from straightforward. To date, no systematic, targeted effort has been made to construct a unifying theory of development. This novel work offers a unique exploration of the foundations of ontogeny by asking how the development of living things should be understood. It explores the key concepts of developmental biology, asks whether general principles of development can be discovered, and examines the role of models and theories. The two editors (one a biologist with long interest in the theoretical aspects of his discipline, the other a philosopher of science who has mainly worked on biological systems) have assembled a team of leading contributors who are representative of the scientific and philosophical community within which a diversity of thoughts are growing, and out of which a theory of development may eventually emerge. They analyse a wealth of approaches to concepts, models and theories of development, such as gene regulatory networks, accounts based on systems biology and on physics of soft matter, the different articulations of evolution and development, symbiont-induced development, as well as the widely discussed concepts of positional information and morphogenetic field, the idea of a 'programme' of development and its critiques, and the long-standing opposition between preformationist and epigenetic conceptions of development. Towards a Theory of Development is primarily aimed at students and researchers in the fields of 'evo-devo', developmental biology, theoretical biology, systems biology, biophysics, and the philosophy of science.

Anschauung denken

Zum Ansatz einer Morphologie des Unmittelbaren
Author: Olaf Breidbach,Federico Vercellone
Publisher: Wilhelm Fink Verlag
ISBN: 3770552490
Category: Aesthetics, Modern
Page: 182
View: 4075

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Bilder schauen wir an, unser Anschauen scheint durch diese Bilder geführt. In der immer stärker anwachsenden Flut solcher Bilder scheint unser Denken mehr und mehr durch dieses Anschauen bestimmt. Dabei offeriert diese Flut meist nur ein Spiel mit bekannten Formen, die variiert und in vielleicht verblüffender Weise präsentiert werden. Oft sind es dabei aber nur Illustrationen, die einen bekannten Gedanken untersetzen. Wo die Bilder aber in Neuland führen, wo sie uns etwas entdecken lassen, ist die Situation anders. Das Bild – und dies interessiert im vorliegenden Band – hat aber seine eigene Logik. Diese Logik ist nicht einfach die, die wir mit dem Bild illustrieren. Es formt sich nach den uns eigenen Anschauungen und leitet uns dann auch in unserem Denken über die Dinge. In ihm meinen wir denn auch Neues entdecken zu können, auf etwas verwiesen zu sein, was wir uns eben nicht schon immer gedacht haben. Wie kommen wir aber eigentlich an solch Neues, wie können wir etwas erkennen, von dem wir noch keinen Begriff haben? Werden wir im Denken solcher Neuigkeiten durch die Anschauung geführt? Greifen wir hier vor das aus, was wir schon begriffen haben? Wenn dies so ist, müssen wir Anschauungen zu denken lernen. Anschauungen zu denken, heißt dann aber nicht einfach zu illustrieren, was wir begriffen haben. Anschauung zu denken, heißt, vor den Begriff zu schauen. Das vorliegende Buch sucht hier nach ersten Antworten.

Morphomechanics of Development


Author: Lev V. Beloussov
Publisher: Springer
ISBN: 3319139908
Category: Science
Page: 195
View: 8844

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This book outlines a unified theory of embryonic development, assuming morphogenesis to be a multi-level process including self-organizing steps while also obeying general laws. It is shown how molecular mechanisms generate mechanical forces, which in the long run lead to morphological changes. Questions such as how stress-mediated feedback acts at the cellular and supra-cellular levels and how executive and regulatory mechanisms are mutually dependent are addressed, while aspects of collective cell behavior and the morphogenesis of plants are also discussed. The morphomechanical approach employed in the book is based on the general principles of self-organization theory.

Animal Evolution

Genomes, Fossils, and Trees
Author: Maximilian J. Telford,D. Timothy J. Littlewood
Publisher: Oxford University Press
ISBN: 0199549427
Category: Science
Page: 245
View: 5837

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Describing and understanding the evolution of the diversity of bodyplans is a major goal of evolutionary biology. Taking a modern, integrated approach to this question, a group of leading researchers describe how modern techniques and disciplines have been combined, resulting in a dramatic renaissance in the study of animal evolution.

General and Systematic Pathology E-Book


Author: James C. E. Underwood,Simon S Cross
Publisher: Elsevier Health Sciences
ISBN: 143772874X
Category: Medical
Page: 860
View: 8156

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This highly acclaimed textbook is written specifically for students of medicine and related health science subjects. It progresses from a review of general pathology principles and disease mechanisms through detailed discussions of the pathologic entities associated with each organ system. Nearly 700 full-color photographs and pathology slides bring the content to life. The fifth edition features extensive updates throughout to reflect the latest discoveries in cellular and molecular pathology, and offers a web site that presents self-assessment material and illustrated clinical case studies. Contents perfectly matches needs on medical students. Very clinical approach matches integrated courses. Extensive International Advisory Board validates contents. Each organ system chapter begins with a brief review of normal structure and function, emphasizing aspects that are important to an understanding of the subsequently discussed disease processes. Offers a superb collection of clinical photographs, histopathology images, and graphics, approximately 700 in all, that richly depict the appearance of both healthy and diseased tissues. New co-editor, Dr Simon Cross. Structure of chapters revised to make the book much easier to use during courses that are problem- or case-based. Several new contributors and re-written chapters. Expanded International Advisory Board.

Genesis


Author: Hermann Gunkel
Publisher: Vandenhoeck & Ruprecht
ISBN: 3525516517
Category: Bible
Page: 527
View: 5214

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Das Evangelium des fliegenden Spaghettimonsters


Author: Bobby Henderson
Publisher: Manhattan
ISBN: 3641182220
Category: Fiction
Page: 240
View: 9384

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Am Anfang war die Nudel – und Bobby Henderson ist ihr Prophet Eine fulminante Satire über religiösen Dogmatismus und die Evolutionstheorie. Zahllose Menschen sind überzeugt zu wissen, wer die Welt erschuf und unsere Geschicke lenkt: Es ist das Fliegende Spaghettimonster. Die Glaubenssätze seiner Anhänger sind klar und überzeugend: Der Pastafarianismus steht für alles, was gut ist. Was lehnt er ab? Alles, was nicht gut ist. Und es ist ein Glaube, der sich im Einklang mit der Wissenschaft befindet. Ob Evolution, Schwerkraft oder globale Erwärmung – das vorliegende Evangelium hält für alles eine bestechend logische Erklärung bereit.

The Design of Everyday Things

Psychologie und Design der alltäglichen Dinge
Author: Norman Don
Publisher: Vahlen
ISBN: 3800648105
Category: Business & Economics
Page: 320
View: 6477

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Apple, Audi, Braun oder Samsung machen es vor: Gutes Design ist heute eine kritische Voraussetzung für erfolgreiche Produkte. Dieser Klassiker beschreibt die fundamentalen Prinzipien, um Dinge des täglichen Gebrauchs umzuwandeln in unterhaltsame und zufriedenstellende Produkte. Don Norman fordert ein Zusammenspiel von Mensch und Technologie mit dem Ziel, dass Designer und Produktentwickler die Bedürfnisse, Fähigkeiten und Handlungsweisen der Nutzer in den Vordergrund stellen und Designs an diesen angepasst werden. The Design of Everyday Things ist eine informative und spannende Einführung für Designer, Marketer, Produktentwickler und für alle an gutem Design interessierten Menschen. Zum Autor Don Norman ist emeritierter Professor für Kognitionswissenschaften. Er lehrte an der University of California in San Diego und der Northwest University in Illinois. Mitte der Neunzigerjahre leitete Don Norman die Advanced Technology Group bei Apple. Dort prägte er den Begriff der User Experience, um über die reine Benutzbarkeit hinaus eine ganzheitliche Erfahrung der Anwender im Umgang mit Technik in den Vordergrund zu stellen. Norman ist Mitbegründer der Beratungsfirma Nielsen Norman Group und hat unter anderem Autohersteller von BMW bis Toyota beraten. „Keiner kommt an Don Norman vorbei, wenn es um Fragen zu einem Design geht, das sich am Menschen orientiert.“ Brand Eins 7/2013 „Design ist einer der wichtigsten Wettbewerbsvorteile. Dieses Buch macht Spaß zu lesen und ist von größter Bedeutung.” Tom Peters, Co-Autor von „Auf der Suche nach Spitzenleistungen“

Genetik für Dummies


Author: Tara Rodden Robinson
Publisher: John Wiley & Sons
ISBN: 3527811478
Category: Science
Page: 400
View: 6686

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Die Genetik ist eine der Naturwissenschaften, deren Wissen am schnellsten wächst und deren Erkenntnisse ständig in Bewegung und in der Diskussion sind. "Genetik für Dummies" erklärt, was überhaupt hinter diesem spannenden Thema steckt. Die Autorin Tara Rodden Robinson erklärt die Grundlagen der Vererbungslehre wie die Mendelschen Regeln, wie Zellen aufgebaut sind und sie sich teilen. Sie zeigt, wie die DNA aufgebaut ist, wie sie kopiert und richtig in Proteine übersetzt wird. Außerdem geht sie auf die Bedeutung der Genetik in der Humanmedizin ein, wie Genmutationen und Erbkrankheiten entstehen. Sie erläutert, was beim Klonen passiert und was sich überhaupt hinter dem Begriff Gentechnik verbirgt. Auch die heißen Themen wie Stammzellentherapie und der Einsatz der Genetik in der Rechtsmedizin werden behandelt.

Behavioral Genetics of the Fly (Drosophila Melanogaster)


Author: Josh Dubnau
Publisher: Cambridge University Press
ISBN: 1139952196
Category: Science
Page: N.A
View: 4500

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The common fruit fly - Drosophila melanogaster - has been the subject of genetics research since the early twentieth century. The complete genomic sequence of Drosophila was published in 2000 and it is still the model organism par excellence for the experimental study of biological phenomena and processes. It is also by far the best model for studying gene function in mammals, including humans. Presenting state-of-the-art studies on the behaviour of Drosophila, this volume discusses normal and pathological models of neurobehavioral disorders and encompasses the specialised methods that have been used, from anatomical, histological, immunohistological and neurophysiological to genomic, genetic and behavioural assays. A comprehensive and thorough reference, this volume is a valuable resource for students and researchers alike across several disciplines of life sciences, including behavioral genetics, neurogenetics, behavioral neuroscience, molecular biology, evolutionary biology and population biology.

The Art of Genes : How Organisms Make Themselves

How Organisms Make Themselves
Author: Enrico Coen
Publisher: Oxford University Press, UK
ISBN: 0191587672
Category: Science
Page: 396
View: 5444

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How is a fertilized egg able to turn itself into an adult? Through a highly original synthesis of science and art, this book vividly describes the recent revolution in our understanding of how plants and animals develop, and the fresh insights this gives us into the nature of evolution and human creativity. - ;How is a tiny fertilised egg able to turn itself into a human being? How can an acorn transform itself into an oak tree? Through a highly original synthesis of science and art, this book vividly describes the recent revolution in our understanding of how plants and animals develop. Drawing on a wide range of material -- from flowers growing petals instead of sex organs, and flies that develop an extra pair of wings, to works by Leonardo and Magritte -- it explains the language and meaning of genes, in an entertaining way that is both accurate and accessible to the general reader. It shows how an organism develops through an interactive dialogue in which there is no clear separation between plan and execution, much as an artist might paint a picture. By explaining how this process has arisen, the book arrives at fresh and exciting insights into the nature of evolution, development and human creativity. -

Gene Expression at the Beginning of Animal Development


Author: Melvin L. DePamphilis
Publisher: Elsevier
ISBN: 9780444510488
Category: Medical
Page: 280
View: 4807

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The beginning of life may be a miracle to some, and a mystery to others, but it is certainly one of the most exciting and perhaps controversial fields of scientific investigation in the 21st century. Among the metazoa, life begins when an egg is fertilized by a sperm. The sperm provides a genetic blueprint from the father and perhaps some critical proteins. The egg provides a genetic blueprint from the mother together with a large reservoir of mRNAs and proteins that are required for DNA replication, cell division and the onset of zygotic gene expression. All of the thousands of genes in these two mature gametes are transcriptionally silent and remain so until fertilization. This work focuses on three biological systems, providing the reader with a clear understanding of the current state of affairs, and the ability to identify common principles as well as critical differences that are responsible for beginning the process of animal development. The essays presented will be of practical value to all those who are interested in improving fertilization in vitro, in designing novel methods of contraception, in developing preimplantation genetic diagnosis for various diseases, in cloning animals by transplanting nuclei from adult cells to an enucleated egg, and in the application of embryonic stem cells to curing genetic diseases or replacing damaged tissues. But above all, this volume is offered to those who simply have an insatiable curiosity about life and its beginnings.