The Handbook of Nanomedicine


Author: Kewal K. Jain
Publisher: Springer Science & Business Media
ISBN: 9781603273190
Category: Science
Page: 404
View: 1078

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This handbook covers the broad scope of nanomedicine. Starting with the basics, the subject is developed to potential clinical applications, many of which are still at an experimental stage. The book features extensive coverage of nanodiagnostics and nanopharmaceuticals, which are two important components of nanomedicine. Written by a physician-scientist author who blends his clinical experience and scientific expertise in new technologies, this book provides a definitive account of nanomedicine. It offers more up-to-date and comprehensive coverage of nanomedicine than any other comparable work.

Handbook of Clinical Nanomedicine

Nanoparticles, Imaging, Therapy, and Clinical Applications
Author: Raj Bawa,Gerald F. Audette,Israel Rubinstein
Publisher: CRC Press
ISBN: 9814669210
Category: Medical
Page: 1708
View: 1484

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This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosimilars and 3D nanofabrication. While bridging the gap between basic biomedical research, engineering, medicine and law, the handbook provides a thorough understanding of nano’s potential to address (i) medical problems from both the patient and health provider's perspective, and (ii) current applications and their potential in a healthcare setting.

Handbook of Clinical Nanomedicine, Two-Volume Set


Author: Raj Bawa,Gerald F. Audette,Israel Rubinstein
Publisher: Pan Stanford
ISBN: 9789814316170
Category: Medical
Page: 800
View: 2856

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The enormous advances in nanomedicine in the past decade have necessitated a growing need for an authoritative and comprehensive reference source that can be relied upon by scientists, clinicians, students, and industry and policy makers alike. The Handbook of Clinical Nanomedicine: From Bench to Bedside is designed to offer a global perspective on the wonders of nanomedicine. The handbook aims to provide a broad survey of various interconnected topics pertaining to nanomedicine. It is intended to be a stand-alone, easily accessible volume that examines the entire "product wheel" from creation of nanomedical products to final market introduction, all accomplished in a user-friendly format. Specifically, everything from bio-nanomaterials and nanodevices from the R&D stage to patent protection, clinical regulatory aspects, and eventual commercialization is encompassed in this book. In addition to highlighting cutting-edge technologies, the book addresses critical topics such as ethics, safety and toxicity, environmental health, nanoeconomics, business strategy, licensing, intellectual property, FDA law, EPA law, and governmental policy issues. With contributions from international experts, the diverse team of editors has compiled a book that provides a unified perspective to these varied topics. While many books focus on nanomedicine, nanotechnology, or nanoscience, none provide the medical applications of nanotechnology with both a clinical and business angle. Furthermore, most of the currently available books on the market fail to highlight the truly global nature of nanomedicine.

Handbook of Harnessing Biomaterials in Nanomedicine

Preparation, Toxicity, and Applications
Author: Dan Peer
Publisher: CRC Press
ISBN: 9814316466
Category: Medical
Page: 424
View: 7134

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This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers, lipids, and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nano-proteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; the use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book covers theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.

Handbook of Materials for Nanomedicine


Author: Vladimir Torchilin,Mansoor M. Amiji
Publisher: Pan Stanford Publishing
ISBN: 9814267589
Category: Medical
Page: 868
View: 1716

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The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.

The Handbook of Nanotechnology

Business, Policy, and Intellectual Property Law
Author: John C. Miller,Ruben Serrato,Jose Miguel Represas-Cardenas,Griffith Kundahl
Publisher: John Wiley & Sons
ISBN: 0471699918
Category: Business & Economics
Page: 384
View: 3037

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In the first attempt to fully explore the controversial issues associated with the commercial application of nanotechnology, you'll find a thorough analysis of intellectual property and patents, financing and legal concerns, regulatory measures particularly in the field of nanomedicine, and environmental regulations. The authors include a set of guideposts you can follow in your due diligence of the business and legal issues pertaining to the technology.

Handbook of Nanophysics

Nanomedicine and Nanorobotics
Author: Klaus D. Sattler
Publisher: CRC Press
ISBN: 9781420075496
Category: Science
Page: 887
View: 8402

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The tools of nanodiagnostics, nanotherapy, and nanorobotics are expected to revolutionize the future of medicine, leading to presymptomatic diagnosis of disease, highly effective targeted treatment therapy, and minimum side effects. Handbook of Nanophysics: Nanomedicine and Nanorobotics presents an up-to-date overview of the application of nanotechnology to molecular and biological processes, medical imaging, targeted drug delivery, and cancer treatment. Each peer-reviewed chapter contains a broad-based introduction and enhances understanding of the state-of-the-art scientific content through fundamental equations and illustrations, some in color. This volume shows how the materials, tools, and techniques of nanotechnology, such as enzymatic nanolithography, biomimetic approaches, and force spectroscopy, are currently used in biological applications, including living cell biochips, biosensors, protein recognition, and the analysis of biomolecules. Drawing on emerging toxicology research, it examines the impact and risks of nanomaterials on human health and the environment. Researchers at the forefront of the field cover tissue engineering, diagnostic, drug delivery, and therapeutic applications, including organs derived from nanomaterials, quantum dots and magnetic nanoparticles for imaging, pharmaceutical nanocarriers, targeted magnetic particles and biodegradable nanoparticles for drug delivery, and cancer treatment using gold nanoparticles. They also explain how cells and skin respond to these nanomaterials. In addition, the book investigates the next generation of nanotechnology research that is focused on nanorobotics and its potential in detecting and destroying cancer cells and detecting and measuring toxic chemicals. It considers the roles nanoheaters, nanomotors, and nanobatteries can play in this new technology. Nanophysics brings together multiple disciplines to determine the structural, electronic, optical, and thermal behavior of nanomaterials; electrical and thermal conductivity; the forces between nanoscale objects; and the transition between classical and quantum behavior. Facilitating communication across many disciplines, this landmark publication encourages scientists with disparate interests to collaborate on interdisciplinary projects and incorporate the theory and methodology of other areas into their work.

Handbook of Nanobiomedical Research

Fundamentals, Applications, and Recent Developments
Author: Vladimir Torchilin
Publisher: World Scientific
ISBN: 9814520659
Category: Technology & Engineering
Page: 2348
View: 7325

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This book consists of 4 volumes containing about 70 chapters covering all the major aspects of the growing area of nanomedicine. Leading scientists from 15 countries cover all major areas of nanobiomedical research materials for nanomedicine, application of nanomedicine in therapy of various diseases, use of nanomedicines for diagnostic purposes, technology of nanomedicines, and new trends in nanobiomedical research. This is the first detailed handbook specifically addressing various aspects of nanobiomedicine. Readers are treated to cutting-edge research and the newest data from leading researchers in this area.Contents: "Materials for Nanomedicine: "Liposomal Nanomedicines "(Amr S Abu Lila, Tatsuhiro Ishida and Theresa M Allen)"Solid Lipid Nanoparticles for Biomedical Applications "(Karsten Mader)"Micellar Nanopreparations for Medicine "(Rupa Sawant and Aditi Jhaveri)"Nanoemulsions in Medicine "(William B Tucker and Sandro Mecozzi)"Drug Nanocrystals and Nanosuspensions in Medicine "(Leena Peltonen, Jouni Hirvonen and Timo Laaksonen)"Polymeric Nanosystems for Integrated Image-Guided Cancer Therapy "(Amit Singh, Arun K Iyer and Mansoor M Amiji)"Polysaccharide-Based Nanocarriers for Drug Delivery "(Carmen Teijeiro, Adam McGlone, Noemi Csaba, Marcos Garcia-Fuentes and Maria J Alonso)"Dendrimers for Biomedical Applications "(Lisa M Kaminskas, Victoria M McLeod, Seth A Jones, Ben J Boyd and Christopher J H Porter)"Layer-by-Layer Nanopreparations for Medicine Smart Polyelectrolyte Multilayer Capsules and Coatings "(Rawil F Fakhrullin, Gleb B Sukhorukov and Yuri M Lvov)"Inorganic Nanopreparations for Nanomedicine "(James Ramos and Kaushal Rege)"Silica-Based Nanoparticles for Biomedical Imaging and Drug Delivery Applications "(Stephanie A Kramer and Wenbin Lin)"Carbon Nanotubes in Biomedical Applications "(Krunal K Mehta, Elena E Paskaleva, Jonathan S Dordick and Ravi S Kane)"Core-Shell Nanoparticles for Biomedical Applications "(Mahmoud Elsabahy and Karen L Wooley)"Structure Activity Relationships for Tumor-Targeting Gold Nanoparticles "(Erik C Dreaden, Ivan H El-Sayed and Mostafa A El-Sayed)"Silver Nanoparticles as Novel Antibacterial and Antiviral Agents "(Stefania Galdiero, Annarita Falanga, Marco Cantisani, Avinash Ingle, Massimiliano Galdiero and Mahendra Rai)"Magnetic Nanoparticles for Drug Delivery "(Rainer Tietze, Harald Unterweger and Christoph Alexiou)"Quantum Dots as a Platform Nanomaterial for Biomedical Applications "(Eleonora Petryayeva, Roza Bidshahri, Kate Liu, Charles A Haynes, Igor L Medintz, and W Russ Algar)""Applications in Therapy: "The Application of Nanomedicine to Cardiovascular Diseases "(Kevin M Bardon, Olivier Kister and Jason R McCarthy)"Nanomedicines for Restenosis Therapy "(J E Tengood, I Fishbein, R J Levy and M Chorny)"Nanopreparations for Cancer Treatment and Diagnostics "(Jayant Khandare, Shashwat Banerjee and Tamara Minko)"Nanoparticles in the Gastrointestinal Tract "(Abraham Rubinstein)"Nanopreparations for Oral Administration "(D Hubbard, D J Brayden and H Ghandehari)"Nanopreparations for Central Nervous System Diseases "(Leyuan Xu and Hu Yang)"Nanoparticles for Dermal and Transdermal Delivery: Permeation Pathways and Applications "(Marianna Foldvari, Marjan Gharagozloo and Christine Li)"Lysosomes and Nanotherapeutics: Diseases, Treatments, and Side Effects "(Rachel L Manthe and Silvia Muro)"Nanostructured Biomaterials for Inhibiting Cancer Cell Functions "(Lijuan Zhang and Thomas J Webster)"Nanomedicine in Otorhinolaryngology"

Handbook of Nanomaterials for Cancer Theranostics


Author: Joao Conde
Publisher: Elsevier
ISBN: 0128133406
Category: Science
Page: 606
View: 1207

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Handbook of Nanomaterials for Cancer Theranostics focuses on recent developments in advanced theranostic nanomedicines from a chemical and biological perspective where the advantages of theranostics are achieved by combining multiple components. The authors explore the pros and cons of theranostic nanomaterials developed in cancer research in the last 15 years, with the different strategies compared and scrutinized. In addition, the book explores how nanomaterials may overcome the regulatory hurdles facing theranostic nanomedicines. This is an important research reference for postgraduates and researchers in nanomedicine and cancer research who want to learn more on how nanomaterials can help create more effective cancer treatments. Highlights the development of smart theranostic nanomaterials to tackle biomedical problems in cancer therapy and diagnostics Explores the regulatory hurdles facing theranostic nanomedicine Discusses how the use of nanomaterials can help create more effective cancer treatments

Handbook of Safety Assessment of Nanomaterials

From Toxicological Testing to Personalized Medicine
Author: Bengt Fadeel
Publisher: CRC Press
ISBN: 981446337X
Category: Medical
Page: 562
View: 5383

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The rapidly evolving field of nanomedicine refers to the clinical application of nanotechnologies. However, as with all new technologies, there are ethical, safety, and regulatory issues. This handbook, written by leading international experts, provides a meticulous overview of the state of the art of safety assessment of nanomaterials (nanotoxicology) in the context of their application in nanomedicine. The volume includes a historical perspective on the development of nanomedicine and its regulation, and a personal view of the future of (nano)medicine by Patrick Hunziker, president of the European Society of Nanomedicine. Ethical considerations in relation to nanomedicine are discussed. There are a series of chapters on organ-specific toxicities of nanomaterials, including pulmonary and cardiovascular toxicity, neurotoxicity, dermatotoxicity, and reproductive toxicity, as well as a discussion on immunotoxicity and genotoxicity. The importance of a thorough characterization of physicochemical properties of nanomaterials is emphasized. The handbook also contains a critical discussion on the applicability of in vitro versus in vivo methods and models for nanosafety assessment, along with an introduction to mathematical modeling approaches with a view to a predictive toxicology of nanomaterials. The overall aim is to provide a comprehensive, science-based framework for safety assessment of current and future nanomedicines.

Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology


Author: Saura C. Sahu,Daniel A. Casciano
Publisher: John Wiley & Sons
ISBN: 1118855868
Category: Science
Page: 440
View: 4895

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The Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology provides an insight into the current trends and future directions of research in these rapidly developing scientific fields. Written by leading scientists and experts, the Handbook will be of interest to various scientific disciplines including toxicology, medicine, and pharmacology, as well as food, drug, and other regulatory sciences.

Immune Aspects of Biopharmaceuticals and Nanomedicines


Author: Raj Bawa,Janos Szebeni,Thomas J Webster,Gerald F. Audette
Publisher: CRC Press
ISBN: 1351399780
Category: Medical
Page: 44
View: 5810

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The enormous advances in the immunologic aspects of biotherapeutics and nanomedicines in the past two decades has necessitated an authoritative and comprehensive reference source that can be relied upon by immunologists, biomedical researchers, clinicians, pharmaceutical companies, regulators, venture capitalists, and policy makers alike. This text provides a thorough understanding of immunology, therapeutic potential, clinical applications, adverse reactions, and approaches to overcoming immunotoxicity of biotherapeutics and nanomedicines. It also tackles critical, yet often overlooked topics such as immune aspects of nano-bio interactions, current FDA regulatory guidances, complement activation-related pseudoallergy (CARPA), advances in nanovaccines, and immunogenicity testing of protein therapeutics.

Handbook of Personalized Medicine

Advances in Nanotechnology, Drug Delivery, and Therapy
Author: Ioannis S. Vizirianakis
Publisher: CRC Press
ISBN: 9814411205
Category: Medical
Page: 1560
View: 6994

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This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.

The Clinical Nanomedicine Handbook


Author: Sara Brenner
Publisher: CRC Press
ISBN: 1439834784
Category: Medical
Page: 365
View: 9160

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Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provides a comprehensive roadmap of the state of nanomedicine in numerous medical specialties Bridges the gap between basic science research, engineering, nanotechnology, and medicine This text discusses what nanomedicine is, how it is currently used, and considers its potential for future applications. It serves as a reference for clinicians, including physicians, nurses, health-care providers, dentists, scientists, and researchers involved in clinical applications of nanotechnology.

Handbook of Immunological Properties of Engineered Nanomaterials


Author: Marina A. Dobrovolskaia,Scott E. McNeil
Publisher: World Scientific
ISBN: 9814390259
Category: Medical
Page: 692
View: 8364

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The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Handbook of Benzoxazine Resins


Author: Hatsuo Ishida,Tarek Agag
Publisher: Elsevier
ISBN: 0444537910
Category: Medical
Page: 712
View: 2813

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This handbook provides a wide overview of the field, fundamental understanding of the synthetic methods and structure/property correlation, as well as studies related to applications in a wide range of subjects. The handbook also provides 1H and 13C NMR spectra, FTIR spectra, DSC and TGA thermograms to aid in research activities. Additional tables on key NMR and FTIR frequencies unique to benzoxazine, heat of polymerization, Tg, and char yield will greatly aid in the choice of proper benzoxazine for a specific application. Provides thorough coverage of the chemistry and applications of benzoxazine resins with an evidence-based approach to enable chemists, engineers and material scientists to evaluate effectiveness Features spectra, which allow researchers to compare results, avoid repetition and save time as well as tables on key NMR frequency, IR frequency, heat of polymerization, of many benzoxazine resins to aid them in selection of materials Written by the foremost experts in the field

Handbook of Functional Nanomaterials

Application and Development
Author: Mahmood Aliofkhazraei
Publisher: Nova Science Pub Incorporated
ISBN: 9781629485669
Category: Technology & Engineering
Page: 531
View: 7961

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This is the third volume of the "Handbook of Functional Nanomaterials" (4 volume set). Functional nanomaterials appear in our daily lives. These materials mainly include nanocomposites, nanopowders, nanoparticles and nanocoatings. Nanotechnology enables the creation of structures that do not exist in nature, those which cannot be produced by conventional chemistry. Some advantages of this technology are the synthesis of stronger, more adjustable materials as well as lower costs. Nanotechnology is scientific and research development at the atomic, molecular, or macromolecular levels in a dimension range of 1 to 100 nm; the fabrication and application of the structures, equipment, and systems which involve unique characteristics and new applications because of their small or medium dimensions; and the potential for the control and management at atomic scales. Therefore, nanotechnology involves industrial research and development at atomic, molecular, and macromolecular levels. This research aims to create and exploit the structures and systems which involve unique applications due to their small dimensions. The main difference between nanotechnology and other technologies is found within the dimensions and properties of the materials and structures applied to this technology. As a matter of fact, the main difference between these two types of technologies is the presence of base elements, which are indeed the same nanoscale elements with different properties in their nanoscale and larger states. Due to the developed properties of the very fine powders including surface chemistry, compressive properties, optical characteristics, and synthetic reactions, as well as an increasing demand for fine powders in industries, a very fine fragmentation is applied in many materials such as: minerals, ceramics, dyes, chemicals, microorganisms, pharmaceuticals and paper manufacturing. This volume mainly discusses the application and development of functional nanomaterials. Some of the functional nanomaterials that were discussed in this volume are titania nanostructures, hybrid nanomaterials based on nanoclays, multifunctional nanomedicine, nanocomposites using polypyrrole, metallic nanoparticles, quantum dots, fullerenes and capped nanotubes, graphene, nanocomposite coatings, functionalized carbon nanotube, nanopowders.

Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering


Author: Soni, Shivani
Publisher: IGI Global
ISBN: 1466663642
Category: Technology & Engineering
Page: 820
View: 900

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As a paradigm for the future, micro-scale technology seeks to fuse revolutionary concepts in science and engineering and then translate it into reality. Nanotechnology is an interdisciplinary field that aims to connect what is seen with the naked eye and what is unseen on the molecular level. The Handbook of Research on Diverse Applications of Nanotechnology in Biomedicine, Chemistry, and Engineering examines the strengths and future potential of micro-scale technologies in a variety of industries. Highlighting the benefits, shortcomings, and emerging perspectives in the application of nano-scale technologies, this book is a comprehensive reference source for synthetic chemists, engineers, graduate students, and researchers with an interest in the multidisciplinary applications, as well as the ongoing research in the field.

Applications of Biotechnology in Neurology


Author: Kewal K. Jain
Publisher: Springer Science & Business Media
ISBN: 162703272X
Category: Medical
Page: 638
View: 476

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Culling together excerpts from a wide range of writings by Dr. Kewal K. Jain on biotechnology topics as they relate to disorders of the nervous system, Applications of Biotechnology in Neurology covers a variety of applications for those working in life sciences and the pharmaceutical sciences, particularly those developing diagnostics and therapeutics for the nervous system. This detailed volume delves into areas such as neurobiotechnology, like neurogenomics and neuroproteomics, molecular diagnostics, various methods of improving systemic administration of drugs for targeted delivery to the nervous system, including the use of nanobiotechnology, biotechnology-based strategies and products for neuroprotection, as well as chapters on neurosurgery and personalized neurology. Thorough, cutting-edge, and thoughtfully organized, Applications of Biotechnology in Neurology serves as an ideal guide, supplemented by 75 tables and 16 figures as well as numerous references from recent literature on this topic, which are appended to each chapter.