The Handbook of Nanomedicine


Author: Kewal K. Jain
Publisher: Humana Press
ISBN: 1493969668
Category: Technology & Engineering
Page: 659
View: 6913

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Nanomedicine is defined as the application of nanobiotechnology in clinical medicine, which is currently being used to research the pathomechanism of disease, refine molecular diagnostics, and aid in the discovery, development, and delivery of drugs. In The Handbook of Nanomedicine, Third Edition, Prof. Kewal K. Jain updates, reorganizes, and replaces information in the comprehensive second edition in order to capture the most recent advances in this dynamic field. Important components of nanomedicine such as drug delivery via nanobiotechnology and nanopharmaceuticals as well as nanooncology, where the greatest number of advances are occurring, are covered extensively. As this text is aimed at nonmedical scientists, pharmaceutical personnel, as well as physicians, descriptions of the technology involved and other medical terminology are kept as clear and simple as possible. In depth and cutting-edge, The Handbook of Nanomedicine, Third Edition informs its readers of the ever-growing field of nanomedicine, destined to play a significant role in the future of healthcare.

Handbook of Materials for Nanomedicine


Author: Vladimir Torchilin,Mansoor M. Amiji
Publisher: Pan Stanford Publishing
ISBN: 9814267589
Category: Medical
Page: 868
View: 9923

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The fast developing field of nanomedicine uses a broad variety of materials to serve as delivery systems for drugs, genes, and diagnostic agents. This book is the first attempt to put under one cover all major available information about these materials, both still on experimental levels and already applied in patients.

Handbook Of Nanobiomedical Research: Fundamentals, Applications And Recent Developments (In 4 Volumes)


Author: Torchilin Vladimir P
Publisher: World Scientific
ISBN: 9814520667
Category: Technology & Engineering
Page: 2352
View: 1344

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This book consists of 4 volumes containing about 70 chapters covering all the major aspects of the growing area of nanomedicine. Leading scientists from 15 countries cover all major areas of nanobiomedical research — materials for nanomedicine, application of nanomedicine in therapy of various diseases, use of nanomedicines for diagnostic purposes, technology of nanomedicines, and new trends in nanobiomedical research.This is the first detailed handbook specifically addressing various aspects of nanobiomedicine. Readers are treated to cutting-edge research and the newest data from leading researchers in this area.

Handbook of Clinical Nanomedicine

Nanoparticles, Imaging, Therapy, and Clinical Applications
Author: Raj Bawa,Gerald F. Audette,Israel Rubinstein
Publisher: CRC Press
ISBN: 9814669210
Category: Medical
Page: 1708
View: 3995

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This handbook (55 chapters) provides a comprehensive roadmap of basic research in nanomedicine as well as clinical applications. However, unlike other texts in nanomedicine, it not only highlights current advances in diagnostics and therapeutics but also explores related issues like nomenclature, historical developments, regulatory aspects, nanosimilars and 3D nanofabrication. While bridging the gap between basic biomedical research, engineering, medicine and law, the handbook provides a thorough understanding of nano’s potential to address (i) medical problems from both the patient and health provider's perspective, and (ii) current applications and their potential in a healthcare setting.

The Clinical Nanomedicine Handbook


Author: Sara Brenner
Publisher: CRC Press
ISBN: 1439834792
Category: Medical
Page: 365
View: 3178

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Designed to foster a stronger awareness and exploration of the subject by practicing clinicians, medical researchers and scientists, The Clinical Nanomedicine Handbook discusses the integration of nanotechnology, biology, and medicine from a clinical point of view. The book highlights relevant research and applications by specialty; it examines nanotechnology in depth, and the potential to solve medical problems. It also increases literacy in nanotechnology, and allows for more effective communication and collaboration between disciplines. Details worldwide developments in nanomedicine Provides a comprehensive roadmap of the state of nanomedicine in numerous medical specialties Bridges the gap between basic science research, engineering, nanotechnology, and medicine This text discusses what nanomedicine is, how it is currently used, and considers its potential for future applications. It serves as a reference for clinicians, including physicians, nurses, health-care providers, dentists, scientists, and researchers involved in clinical applications of nanotechnology.

Handbook of Harnessing Biomaterials in Nanomedicine

Preparation, Toxicity, and Applications
Author: Dan Peer
Publisher: CRC Press
ISBN: 9814316466
Category: Medical
Page: 424
View: 5448

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This book concentrates on the use of biomaterials in nanomedicine. The areas of focus include drug delivery by polymers, lipids, and carbohydrates for the delivery of small molecules, RNA interference, and proteins; the use of nano-proteins such as antibodies and peptides as targeting agents for therapeutics and diagnosis; the use of nanocarrier-based biomaterials for manipulation of stem cells; different aspects of toxicity of nanocarriers (the immune response, liver toxicity, and many more); and success stories of biomaterials that have reached the clinics. The book covers theoretical and experimental analysis of various biomaterials that are used in nanomedicine, research methods and preparation techniques, and several promising applications.

Handbook of Immunological Properties of Engineered Nanomaterials


Author: Marina A. Dobrovolskaia,Scott E. McNeil
Publisher: World Scientific
ISBN: 9814390259
Category: Medical
Page: 692
View: 9673

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The Handbook of Immunological Properties of Engineered Nanomaterials provides a comprehensive overview of the current literature, methodologies, and translational and regulatory considerations in the field of nanoimmunotoxicology. The main subject is the immunological properties of engineered nanomaterials. Focus areas include interactions between engineered nanomaterials and red blood cells, platelets, endothelial cells, professional phagocytes, T cells, B cells, dendritic cells, complement and coagulation systems, and plasma proteins, with discussions on nanoparticle sterility and sterilization. Each chapter presents a broad literature review of the given focus area, describes protocols and resources available to support research in the individual focus areas, highlights challenges, and outlines unanswered questions and future directions. In addition, the Handbook includes an overview of and serves a guide to the physicochemical characterization of engineered nanomaterials essential to conducting meaningful immunological studies of nanoparticles. Regulations related to immunotoxicity testing of materials prior to their translation into the clinic are also reviewed.The Handbook is written by top experts in the field of nanomedicine, nanotechnology, and translational bionanotechnology, representing academia, government, industry, and consulting organizations, and regulatory agencies. The Handbook is designed to serve as a textbook for students, a practical guide for research laboratories, and an informational resource for scientific consultants, reviewers, and policy makers. It is written such that both experts and beginners will find the information highly useful and applicable.

Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology


Author: Saura C. Sahu,Daniel A. Casciano
Publisher: John Wiley & Sons
ISBN: 1118855868
Category: Science
Page: 440
View: 877

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The Handbook of Nanotoxicology, Nanomedicine and Stem Cell Use in Toxicology provides an insight into the current trends and future directions of research in these rapidly developing scientific fields. Written by leading scientists and experts, the Handbook will be of interest to various scientific disciplines including toxicology, medicine, and pharmacology, as well as food, drug, and other regulatory sciences.

Handbook of Clinical Nanomedicine, Two-Volume Set


Author: Raj Bawa,Gerald F. Audette,Israel Rubinstein
Publisher: Pan Stanford
ISBN: 9789814316170
Category: Medical
Page: 800
View: 6035

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The enormous advances in nanomedicine in the past decade have necessitated a growing need for an authoritative and comprehensive reference source that can be relied upon by scientists, clinicians, students, and industry and policy makers alike. The Handbook of Clinical Nanomedicine: From Bench to Bedside is designed to offer a global perspective on the wonders of nanomedicine. The handbook aims to provide a broad survey of various interconnected topics pertaining to nanomedicine. It is intended to be a stand-alone, easily accessible volume that examines the entire "product wheel" from creation of nanomedical products to final market introduction, all accomplished in a user-friendly format. Specifically, everything from bio-nanomaterials and nanodevices from the R&D stage to patent protection, clinical regulatory aspects, and eventual commercialization is encompassed in this book. In addition to highlighting cutting-edge technologies, the book addresses critical topics such as ethics, safety and toxicity, environmental health, nanoeconomics, business strategy, licensing, intellectual property, FDA law, EPA law, and governmental policy issues. With contributions from international experts, the diverse team of editors has compiled a book that provides a unified perspective to these varied topics. While many books focus on nanomedicine, nanotechnology, or nanoscience, none provide the medical applications of nanotechnology with both a clinical and business angle. Furthermore, most of the currently available books on the market fail to highlight the truly global nature of nanomedicine.

Polymer Nanoparticles for Nanomedicines

A Guide for their Design, Preparation and Development
Author: Christine Vauthier,Gilles Ponchel
Publisher: Springer
ISBN: 3319414216
Category: Medical
Page: 638
View: 3288

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This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.

Handbook of Personalized Medicine

Advances in Nanotechnology, Drug Delivery, and Therapy
Author: Ioannis S. Vizirianakis
Publisher: CRC Press
ISBN: 9814411205
Category: Medical
Page: 1560
View: 3126

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This book compiles multidisciplinary efforts to conceptualize the environment in research and clinical setting that creates the fertile ground for the practical utility of personalized medicine decisions and also enables clinical pharmacogenomics for establishing pharmacotyping in drug prescription. Its covers innovative drug formulations and nanotheranostics, molecular imaging and signatures, translational nanomedicine and informatics, stem cell therapy approaches, modeling and predictability of drug response, pharmacogenetics-guided drug prescription, pediatric drug dosing, pharmacovigilance and regulatory aspects, ethical and cost-effectiveness issues, pharmacogenomics knowledge bases, personal genome sequencing, molecular diagnostics, as well as information-based medicine.

Handbook of Safety Assessment of Nanomaterials

From Toxicological Testing to Personalized Medicine
Author: Bengt Fadeel
Publisher: CRC Press
ISBN: 9814463361
Category: Medical
Page: 562
View: 7922

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The rapidly evolving field of nanomedicine refers to the clinical application of nanotechnologies. However, as with all new technologies, there are ethical, safety, and regulatory issues. This handbook, written by leading international experts, provides a meticulous overview of the state of the art of safety assessment of nanomaterials (nanotoxicology) in the context of their application in nanomedicine. The volume includes a historical perspective on the development of nanomedicine and its regulation, and a personal view of the future of (nano)medicine by Patrick Hunziker, president of the European Society of Nanomedicine. Ethical considerations in relation to nanomedicine are discussed. There are a series of chapters on organ-specific toxicities of nanomaterials, including pulmonary and cardiovascular toxicity, neurotoxicity, dermatotoxicity, and reproductive toxicity, as well as a discussion on immunotoxicity and genotoxicity. The importance of a thorough characterization of physicochemical properties of nanomaterials is emphasized. The handbook also contains a critical discussion on the applicability of in vitro versus in vivo methods and models for nanosafety assessment, along with an introduction to mathematical modeling approaches with a view to a predictive toxicology of nanomaterials. The overall aim is to provide a comprehensive, science-based framework for safety assessment of current and future nanomedicines.

Handbook of Nanophysics

Nanomedicine and Nanorobotics
Author: Klaus D. Sattler
Publisher: CRC Press
ISBN: 9781420075496
Category: Science
Page: 887
View: 9115

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The tools of nanodiagnostics, nanotherapy, and nanorobotics are expected to revolutionize the future of medicine, leading to presymptomatic diagnosis of disease, highly effective targeted treatment therapy, and minimum side effects. Handbook of Nanophysics: Nanomedicine and Nanorobotics presents an up-to-date overview of the application of nanotechnology to molecular and biological processes, medical imaging, targeted drug delivery, and cancer treatment. Each peer-reviewed chapter contains a broad-based introduction and enhances understanding of the state-of-the-art scientific content through fundamental equations and illustrations, some in color. This volume shows how the materials, tools, and techniques of nanotechnology, such as enzymatic nanolithography, biomimetic approaches, and force spectroscopy, are currently used in biological applications, including living cell biochips, biosensors, protein recognition, and the analysis of biomolecules. Drawing on emerging toxicology research, it examines the impact and risks of nanomaterials on human health and the environment. Researchers at the forefront of the field cover tissue engineering, diagnostic, drug delivery, and therapeutic applications, including organs derived from nanomaterials, quantum dots and magnetic nanoparticles for imaging, pharmaceutical nanocarriers, targeted magnetic particles and biodegradable nanoparticles for drug delivery, and cancer treatment using gold nanoparticles. They also explain how cells and skin respond to these nanomaterials. In addition, the book investigates the next generation of nanotechnology research that is focused on nanorobotics and its potential in detecting and destroying cancer cells and detecting and measuring toxic chemicals. It considers the roles nanoheaters, nanomotors, and nanobatteries can play in this new technology. Nanophysics brings together multiple disciplines to determine the structural, electronic, optical, and thermal behavior of nanomaterials; electrical and thermal conductivity; the forces between nanoscale objects; and the transition between classical and quantum behavior. Facilitating communication across many disciplines, this landmark publication encourages scientists with disparate interests to collaborate on interdisciplinary projects and incorporate the theory and methodology of other areas into their work.

Springer Handbook of Nanomaterials


Author: Robert Vajtai
Publisher: Springer Science & Business Media
ISBN: 364220595X
Category: Technology & Engineering
Page: 1221
View: 7666

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The Springer Handbook of Nanomaterials covers the description of materials which have dimension on the "nanoscale". The description of the nanomaterials in this Handbook follows the thorough but concise explanation of the synergy of structure, properties, processing and applications of the given material. The Handbook mainly describes materials in their solid phase; exceptions might be e.g. small sized liquid aerosols or gas bubbles in liquids. The materials are organized by their dimensionality. Zero dimensional structures collect clusters, nanoparticles and quantum dots, one dimensional are nanowires and nanotubes, while two dimensional are represented by thin films and surfaces. The chapters in these larger topics are written on a specific materials and dimensionality combination, e.g. ceramic nanowires. Chapters are authored by well-established and well-known scientists of the particular field. They have measurable part of publications and an important role in establishing new knowledge of the particular field.

Textbook of Personalized Medicine


Author: Kewal K. Jain
Publisher: Humana Press
ISBN: 1493925539
Category: Medical
Page: 732
View: 8672

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Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews the fundamentals and development of personalized medicine and subsequent adoptions of the concepts by the biopharmaceutical industry and the medical profession. It also discusses examples of applications in key therapeutic areas, as well as ethical and regulatory issues, providing a concise and comprehensive source of reference for those involved in healthcare management, planning and politics. Algorithms are included as a guide to those involved in the management of important diseases where decision-making is involved due to the multiple choices available. Textbook of Personalized Medicine, Second Edition will serve as a convenient source of information for physicians, scientists, decision makers in the biopharmaceutical and healthcare industries and interested members of the public.

Introduction to Nanomedicine and Nanobioengineering


Author: Paras N. Prasad
Publisher: John Wiley & Sons
ISBN: 111835107X
Category: Science
Page: 608
View: 4336

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This book is an introduction to the emerging field of nanomedicine and its applications to health care. It describes the many multidisciplinary challenges facing nanomedicine and discusses the required collaboration between chemists, physicists, engineers and clinicians. The book introduces the reader to nanomedicine's vast potential to improve and extend human life through the application of nanomaterials in diagnosis and treatment of disease.

Nanomedicine

Principles and Perspectives
Author: Yi Ge,Songjun Li,Shenqi Wang,Richard Moore
Publisher: Springer
ISBN: 1461421403
Category: Science
Page: 413
View: 1577

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Increasing demand for and awareness of the applications of nanotechnology in medicine has resulted in the emergence of a new fast-growing multidisciplinary area - nanomedicine. This book offers comprehensive knowledge of and diverse perspectives on nanomedicine through two independent volumes. It aims to bridge the gap between nanotechnology and medicine through contributions by world-renowned experts from wide range of backgrounds including academia, industry, professional consultancy, and government agencies. Each contribution integrates knowledge from a wide range of areas to present the fundamentals of new applications and products of nanomedicine, as well as an outlook for the future. This book can well serve as a reference and guide for students, academics, researchers, scientists, engineers, clinicians, government researchers, and healthcare professionals.

Nanomedicine for Cancer Therapy

From Chemotherapeutic to Hyperthermia-Based Therapy
Author: Piyush Kumar,Rohit Srivastava
Publisher: Springer
ISBN: 3319458264
Category: Technology & Engineering
Page: 68
View: 2525

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This Brief focuses on the cancer therapy available till date, from conventional drug delivery to nanomedicine in clinical trial. In addition, it reports on future generation based nanotherapeutics and cancer theranostic agent for effective therapeutic diagnosis and treatment. Breast cancer was chosen as the model system in this review. The authors give emphasis to multiple drug resistance (MDR) and its mechanism and how to overcome it using the nanoparticle approach.

Nanoparticle Technology Handbook


Author: Makio Naito,Toyokazu Yokoyama,Kouhei Hosokawa,Kiyoshi Nogi
Publisher: Elsevier
ISBN: 0444641114
Category: Technology & Engineering
Page: 904
View: 1451

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Nanoparticle Technology Handbook, Third Edition, is an updated and expanded authoritative reference providing both the theory behind nanoparticles and the practical applications of nanotechnology. This third edition features twenty new chapters, providing a reference much broader in scope than the previous edition. Over 140 experts in nanotechnology and/or particle technology contributed to this new edition. The book not only includes the theory behind nanoparticles, but also the practical applications of nanotechnology. It examines future possibilities and new innovations and contains important knowledge on nanoparticle characterization and the effect of nanoparticles on the environment and humans. Nanoparticle technology is a new and revolutionary technology, which is increasingly used in electronic devices and nanomaterials. It handles the preparation, processing, application and characterization of nanoparticles and has become the core of nanotechnology as an extension of conventional fine particle/powder technology. Nanoparticle technology plays an important role in the implementation of nanotechnology in many engineering and industrial fields, including electronic devices, advanced ceramics, new batteries, engineered catalysts, functional paint and ink, drug delivery system, biotechnology, etc., making use of the unique properties of nanoparticles, which are completely different from those of bulk materials. Introduces all aspects of nanoparticle technology, from the fundamentals to applications Cover basic information on preparation through to the characterization of nanoparticles in a systematic way Features information on nanostructures, which play an important role in practical applications Includes the effects of nanoparticles on human health and the environment Includes applications of nanoparticles in diverse fields, including applications in new areas, such as electronics cosmetics, etc. Offers up-to-date information given by specialists in each field

Handbook of Small Animal Imaging

Preclinical Imaging, Therapy, and Applications
Author: George C. Kagadis,Nancy L. Ford,Dimitrios N. Karnabatidis,George K. Loudos
Publisher: CRC Press
ISBN: 1498785743
Category: Medical
Page: 602
View: 7309

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The use of small animal models in basic and preclinical sciences constitutes an integral part of testing new pharmaceutical agents prior to their application in clinical practice. New imaging and therapeutic approaches need to be tested and validated first in animals before application to humans. Handbook of Small Animal Imaging: Preclinical Imaging, Therapy, and Applications collects the latest information about various imaging and therapeutic technologies used in preclinical research into a single source. Useful to established researchers as well as newcomers to the field, this handbook shows readers how to exploit and integrate these imaging and treatment modalities and techniques into their own research. The book first presents introductory material on small animal imaging, therapy, and research ethics. It next covers ionizing radiation and nonionizing radiation methods in small animal imaging, hybrid imaging, and imaging agents. The book then addresses therapeutic research platforms and image quantification, explaining how to ensure accurate measurements of high-quality data. It concludes with an overview of many small animal imaging and therapy applications that demonstrate the strength of the techniques in biomedical fields.