The Analytical Chemistry of Cannabis

Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations
Author: Brian F Thomas,Mahmoud ElSohly
Publisher: Elsevier
ISBN: 0128046708
Category: Science
Page: 132
View: 2479

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A volume in the Emerging Issues in Analytical Chemistry series, The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations provides analytical chemistry methods that address the latest issues surrounding cannabis-based products. The plethora of marketed strains of cannabis and cannabinoid-containing products, combined with the lack of industry standards and labelling requirements, adds to the general perception of poor quality control and limited product oversight. The methods described in this leading-edge volume help to support the manufacturing, labelling, and distribution of safe and consistent products with known chemical content and demonstrated performance characteristics. It treats analytical chemistry within the context of the diverse issues surrounding medicinal and recreational cannabis in a manner designed to foster understanding and rational perspective in non-scientist stakeholders as well as scientists who are concerned with bringing a necessary degree of order to a field now characterized by confusion and contradiction. The Emerging Issues in Analytical Chemistry series is published in partnership with RTI International and edited by Brian F. Thomas. Please be sure to check out our other featured volumes: Hackney, Anthony C. Exercise, Sport, and Bioanalytical Chemistry: Principles and Practice, 9780128092064, March 2016. Tanna, Sangeeta and Lawson, Graham. Analytical Chemistry for Assessing Medication Adherence, 9780128054635, April 2016. Rao, Vikram, Knight, Rob, and Stoner, Brian. Sustainable Shale Oil and Gas: Analytical Chemistry, Biochemistry, and Geochemistry Methods, 9780128103890, forthcoming September 2016. Farsalinos, Konstantinos, et al. Analytical Assessment of e-Cigarettes: From Contents to Chemical and Particle Exposure Profiles, 9780128112410, forthcoming November 2016. Addresses current and emerging analytical chemistry methods—an approach that is unique among the literature on this topic Presents information from a broad perspective of the issues in a single compact volume Employs language comprehensible to non-technical stakeholders as well as to specialists in analytical chemistry

Detection of Drugs and Their Metabolites in Oral Fluid


Author: Robert M. White,Christine M. Moore
Publisher: Elsevier
ISBN: 012814596X
Category: Science
Page: 140
View: 3926

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Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends. This volume covers the salient aspects of oral fluid drug testing, including specimen collection and handling, initial testing, point of collection testing (POCT), specimen validity testing (SVT), and confirmatory and proficiency testing. Analytes discussed include amphetamines, cannabinoids, cocaine, opiates, phencyclidine, cannabimimetics, and miscellaneous drugs. This practical guide helps users turn knowledge into practice, moving logically from an outline of the problem, to the evaluation of the appropriateness of oral fluid as a test medium, and finally to a consideration of detection methods and their validation and employment. Compares different collection and testing systems to assist readers involved in clinical or forensic practice in selecting oral fluid as the matrix of choice Provides a sound basis for the detection of drugs and their metabolites in oral fluid and the interpretation of both positive and negative Places the need, or lack thereof, for specimen validity testing and confirmation testing in context with the purposes of oral fluid testing Describes drugs and drug classes that can be tested, along with useful information on a patient/donor’s drug status

Doping, Performance-Enhancing Drugs, and Hormones in Sport

Mechanisms of Action and Methods of Detection
Author: Anthony C Hackney
Publisher: Elsevier
ISBN: 0128134437
Category: Science
Page: 168
View: 6845

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Doping, Performance-Enhancing Drugs, and Hormones in Sport: Mechanisms of Action and Methods of Detection examines the biochemistry and bioanalytical aspects of performance-enhancing drugs (PEDs) and other questionable procedures used by athletes to enhance performance. The book informs the specialist of emerging knowledge and techniques and allows the non-specialist to grasp the underlying science and current practice of the discipline. With clear and compelling language appropriate for a broad spectrum of readers, this book provides background on prevalence, types of agents, their actual or supposed benefits, and their negative effects on health. The technical aspects of detection are discussed, followed by a discussion of why detection is a problematic and still-evolving science. To facilitate comprehension, each chapter is organized in a uniform way with six sections: (1) standard medical uses, (2) why the drugs are used by athletes, (3) biological mechanism of action, (4) what research says about efficacy in improving performance, (5) major health side effects from use and abuse in sport, and 6) concluding key points. Presents the scientific concepts of how performance enhancers work, how they are used, and how they are detected and masked from detection Features language that is neither simplistic to scientists nor too sophisticated for a large, diverse global audience Provides a short “close-up” in each chapter to illustrate key topics that engage, entertain, and create a novel synthesis of thought

Inhaled Pharmaceutical Product Development Perspectives

Challenges and Opportunities
Author: Anthony J. Hickey
Publisher: Elsevier
ISBN: 0128123362
Category: Science
Page: 110
View: 5200

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Inhaled Pharmaceutical Product Development Perspectives: Challenges and Opportunities describes methods and procedures for consideration when developing inhaled pharmaceuticals, while commenting on product development strategies and their suitability to support regulatory submission. It bridges the gap between the aspirations of scientists invested in new technology development and the requirements that must be met for any new product. The book brings together emerging analytical and inhalation technologies, providing perspectives that illuminate formulation and device design, development, regulatory compliance, and practice. Focusing on underlying scientific and technical principles known to be acceptable from the current regulatory perspective, this monograph will remain useful as a high-level guide to inhaled product development for the foreseeable future. Discusses development strategies and best practices in the context of regulatory requirements Written by a broadly qualified expert drawing on the knowledge and critical opinions of key individuals in the field Includes a foreword by Charles G. Thiel

Analytical Chemistry for Assessing Medication Adherence


Author: Sangeeta Tanna,Graham Lawson
Publisher: Elsevier
ISBN: 012805459X
Category: Science
Page: 156
View: 496

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The lack of adherence to medication is a growing public health problem worldwide and is costing many patients their good health and healthcare systems billions of dollars. A new volume in the Emerging Issues in Analytical Chemistry series, Analytical Chemistry for Assessing Medication Adherence introduces the concept of medication adherence/compliance and reports international perspectives on medication adherence while highlighting its importance. It then describes the opportunities for analytical chemistry to assess medication adherence and thereby provide an evidence base for clinicians to improve patient health outcomes. The authors highlight the strengths and weaknesses of each of the analytical techniques cited in addition to categorizing the findings in terms of the biological samples used to assess adherence and identifying methods to extract biological samples prior to analysis. The final chapter provides the authors’ perspective in this area, emphasising the importance of medication optimization for individual patients. The Emerging Issues in Analytical Chemistry series is published in partnership with RTI International and edited by Brian F. Thomas. Please be sure to check out our other featured volumes: Thomas, Brian F. and ElSohly, Mahmoud. The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations, 9780128046463, December 2015. Hackney, Anthony C. Exercise, Sport, and Bioanalytical Chemistry: Principles and Practice, 9780128092064, March 2016. Rao, Vikram, Knight, Rob, and Stoner, Brian. Sustainable Shale Oil and Gas: Analytical Chemistry, Biochemistry, and Geochemistry Methods, 9780128103890, forthcoming September 2016. Farsalinos, Konstantinos, et al. Analytical Assessment of e-Cigarettes: From Contents to Chemical and Particle Exposure Profiles, 9780128112410, forthcoming November 2016. Surveys the strengths, weaknesses, and appropriateness of existing instruments and techniques and points the way toward a program of therapeutic optimization Brings together data scattered amongst professional journals and other sources in a single convenient volume Presents the problem of adherence and the authors’ evaluation of possible solutions based on the analysis of patient bio-samples

Exercise, Sport, and Bioanalytical Chemistry

Principles and Practice
Author: Anthony C Hackney
Publisher: Elsevier
ISBN: 0128096918
Category: Science
Page: 136
View: 2980

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A new volume in the Emerging Issues in Analytical Chemistry series, Exercise, Sport, and Bioanalytical Chemistry: Principles and Practice focuses on the basic and applied aspects of energy metabolism in humans. Concise and scientific, yet intelligible to the nonscientist, the book consists of two parts. Part I, Introduction: Basics and Background, provides the biochemistry necessary to understand the rest of the book and describes analytical processes and results as an aid to grasping the science. Part II, Applications: Knowledge into Practice, explores measurement techniques for metabolism, energy expenditure of various activities, techniques that enhance expenditure, metabolic adaptation, foods and drugs that enhance expenditure, and the role of bioanalytical chemistry in future research in exercise and sport. Discussion of the benefits of exercise and practices for improving the capacity to perform exercise is illustrated by many useful and entertaining examples. This volume allows readers to come away with a grasp of the scientific concepts, how they are manifested in research techniques, and how the results of research can be applied in the real world of public health and personal development. The Emerging Issues in Analytical Chemistry series is published in partnership with RTI International and edited by Brian F. Thomas. Please be sure to check out our other featured volumes: Thomas, Brian F. and ElSohly, Mahmoud. The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations, 9780128046463, December 2015. Tanna, Sangeeta and Lawson, Graham. Analytical Chemistry for Assessing Medication Adherence, 9780128054635, April 2016. Rao, Vikram, Knight, Rob, and Stoner, Brian. Sustainable Shale Oil and Gas: Analytical Chemistry, Biochemistry, and Geochemistry Methods, 9780128103890, forthcoming September 2016. Farsalinos, Konstantinos, et al. Analytical Assessment of e-Cigarettes: From Contents to Chemical and Particle Exposure Profiles, 9780128112410, forthcoming November 2016. Provides readers with the fundamental biochemistry and some elements of the physiology behind physical activity/exercise and describes the analytical techniques used to elucidate the science Written in clear, concise, compelling prose that is neither simplistic to scientists nor too sophisticated for a large, diverse global audience A one-page Close-Up in each chapter illustrates key topics to catch, engage, entertain, and create a novel synthesis of thought

Analytical Assessment of e-Cigarettes

From Contents to Chemical and Particle Exposure Profiles
Author: Konstantinos E. Farsalinos,I. Gene Gillman,Stephen S. Hecht,Riccardo Polosa,Jonathan Thornburg
Publisher: Elsevier
ISBN: 0128112425
Category: Medical
Page: 162
View: 3414

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A volume in the Emerging Issues in Analytical Chemistry series, Analytical Assessment of E-Cigarettes: From Contents to Chemical and Particle Exposure Profiles addresses the many issues surrounding electronic cigarettes in an unprecedented level of scientific detail. The plethora of product devices, formulations, and flavors, combined with the lack of industry standards and labeling requirements, quality control, and limited product oversight, has given rise to public concern about initiation of use and potential for adverse exposure and negative long-term health outcomes. This volume discusses how analytical methods can address these issues and support the manufacturing, labeling, distribution, testing, regulation, and monitoring for consistency of products with known chemical content and demonstrated performance characteristics. The book begins with the background on aerosol drug delivery services and e-cigarettes, constituents of nicotine-containing liquid dosing formulations, typical use scenarios and associated aerosol emissions, and chemical exposures and pharmacological and toxicological effect profiles, and then continues with descriptions of the analytical methods used to characterize the chemicals in formulations and emissions from e-cigarettes, including their stability, physical particle-size distribution and thermal degradation under commonly employed conditions of use. Analytical methods enabling detection of biomarkers of exposure and harm in complex biological matrices are discussed, with an emphasis on constituents or emissions of current medicinal interest or with potential to produce harm. Opportunities and challenges for analytical chemistry in supporting the continued development and use of safe and consistent dosage formulations as alternatives to tobacco products are also explored, with a concluding section describing an analytical approach to a risk-benefit assessment of e-cigarette use on human health. The Emerging Issues in Analytical Chemistry series is published in partnership with RTI International and edited by Brian F. Thomas. Please be sure to check out our other featured volumes: Thomas, Brian F. and ElSohly, Mahmoud. The Analytical Chemistry of Cannabis: Quality Assessment, Assurance, and Regulation of Medicinal Marijuana and Cannabinoid Preparations, 9780128046463, December 2015. Hackney, Anthony C. Exercise, Sport, and Bioanalytical Chemistry: Principles and Practice, 9780128092064, March 2016. Tanna, Sangeeta and Lawson, Graham. Analytical Chemistry for Assessing Medication Adherence, 9780128054635, April 2016. Rao, Vikram; Knight, Rob; and Stoner, Brian. Sustainable Shale Oil and Gas: Analytical Chemistry, Biochemistry, and Geochemistry Methods, 9780128103890, September 2016. Discusses the chemistry and physics involved in aerosol production, inhalation, deposition, chemical exposure, and effect assessment Contains current information and state-of-the-science methods on e-cigarette emissions, exposures, and harm assessment Offers an authoritative, objective perspective from five of the most well-recognized scientists in their areas of expertise who have no personal stake in the e-cigarette industry or the opposition Includes a foreword written by Dr. Neal Benowitz

Methods and Advances in Traditional Chinese Medicine


Author: David Yue-Wei Lee,Kai-Shun Bi,Gerald T. Pollard,Ronghua Dai
Publisher: N.A
ISBN: 9780128051610
Category:
Page: 150
View: 5815

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Methods and Advances in Traditional Chinese Medicine describes analytical chemistry methods used to characterize constituents of herbal remedies, explore their mechanisms of action singly and in concert, and support the clinical trials necessary to bring Traditional Chinese Medicine (TCM) into the mainstream of therapeutics. With recent advances in analytical instruments, molecular pharmacology, and genetics, it is now possible to investigate the bioactive molecules in a complex medicine on a rational basis. This book is the first to combine TCM with analytical chemistry methods toward this goal. The book begins with a brief history of TCM, consideration of its strengths and weaknesses, and a review of the literature on application of Western analytical methods. It continues with an examination of the concept of synergistic, multi-targeted action among components, followed by an analysis of how analytical chemistry and other methods are used to assure quality and uniformity of natural products within tolerable limits. It then addresses the complexity introduced by absorption, distribution, and metabolism of an already complex drug. The last chapter advocates a system biological approach as the way forward for drug discovery and development in TCM. Emphasizes the advantages of combining traditional medicine and modern tools for drug discovery and development Provides examples which source, identify, and assay materials; describe preparation of complex remedies and isolate or synthesize their components; characterize complexes and derivatives; and test selected entities for efficacy in animals and humans Explains the capabilities and limitations of various methods for evaluating test results, establishing the parameters of quality assurance

Beurteilungskriterien

Urteilsbildung in der medizinisch-psychologischen Fahreignungsdiagnostik
Author: Wolfgang Schubert
Publisher: N.A
ISBN: 9783781216785
Category: Fahreignungsdiagnostik
Page: 228
View: 1148

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Cannabis und Cannabinoide

Pharmakologie, Toxikologie und therapeutisches Potenzial
Author: Franjo Grotenhermen
Publisher: N.A
ISBN: 9783456841052
Category: Cannabinoide - Aufsatzsammlung
Page: 509
View: 6194

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Die künstlichen Paradiese


Author: Charles Baudelaire
Publisher: BoD – Books on Demand
ISBN: 3862671739
Category: Fiction
Page: 92
View: 4313

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In seinem Essay "Die künstlichen Paradiese" (1860) setzt Baudelaire sich mit der Wirkung bewusstseinserweiternder Drogen und ihrer Bedeutung für die Dichteridentität und das künstlerische Schaffen auseinander. Der französische Autor hatte selber mit Alkohol, Haschisch und Opium experimentiert, um seinem Geist und seinen Sinnen neue Erfahrungswelten zu eröffnen. Er musste jedoch erkennen, dass der Drogenkonsum seine künstlerische Produktivität nur bedingt zu steigern vermochte, und eine dauerhafte Flucht aus dem Alltag nicht möglich war. Wie auch andere große Schriftsteller mit Drogenerfahrungen, z. B. Edgar Allan Poe und Ernst Jünger, beschreibt Baudelaire das ambivalente Verhältnis zu seinen Rauscherfahrungen und die Enttäuschung angesichts ihres begrenzten Stimulus.

Papyros Ebers

Das älteste Buch über Heilkunde
Author: H. Joachim
Publisher: Walter de Gruyter GmbH & Co KG
ISBN: 3111521761
Category: History
Page: 234
View: 1209

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Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition


Author: N.A
Publisher: ScholarlyEditions
ISBN: 1464963444
Category: Medical
Page: 4229
View: 7038

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Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Pharmacology, Pharmacy, Drug Research, and Drug Innovation. The editors have built Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Pharmacology, Pharmacy, Drug Research, and Drug Innovation in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Pharmacology, Pharmacy, Drug Research, and Drug Innovation: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Kriminaltechnik

mit der Wissenschaft auf Verbrecherjagd
Author: Brian H. Kaye
Publisher: N.A
ISBN: 9783933203953
Category:
Page: 323
View: 9699

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Immunoassays


Author: Arnold Raem,Peter Rauch
Publisher: Spektrum Akademischer Verlag
ISBN: 9783827416360
Category: Medical
Page: 370
View: 2253

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Immunoassays, wie ELISA, Western Blots, Immuno-PCR oder Flow-Cytometrie, kommt in der Diagnostik eine große und ständig wachsende Bedeutung zu. Dieses Methodenbuch vermittelt eine gut lesbare, fundierte Einführung in die Grundprinzipien, so dass sich Wissenschaftler der Naturwissenschaften und Medizin wie auch TAs einen ersten, grundlegenden Einblick in die Durchführung der verschiedenen Immunoassays verschaffen können, über deren unterschiedliche Einsatzbereiche, aber auch mit Problemen, Statistik und Validierung konfrontiert werden. Besonders hervorzuheben in diesem Buch sind die akkuraten und funktionierenden Rezepte. Durch ihre tagtägliche Arbeit mit Immunoassays verfügen die Autoren wie auch die Herausgeber über einen reichen Erfahrungsschatz mit diesen Methoden.