Guidelines for laboratory design

health and safety considerations
Author: Louis J. DiBerardinis
Publisher: Wiley-Interscience
ISBN: 9780471254478
Category: Architecture
Page: 612
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The construction of new laboratory buildings or the renovation of existing ones requires close communication between laboratory users, project engineers, architects, construction engineers, and health and safety personnel. All too often, health and safety considerations are overlooked or slighted and are not sufficiently incorporated into designs. Guidelines for Laboratory Design: Health and Safety Considerations, Third Edition provides reliable design information related to specific health and safety issues that need to be considered when building or renovating laboratories. With an increase in the number of laboratory renovations due to lower costs and faster end results compared to constructing new buildings, the latest edition of Guidelines for Laboratory Design, which includes new chapters on laboratory renovation, is particularly timely. This well-established and respected volume also includes a vital section on design guidelines for commonly used laboratories and features separate chapters on a wide array of laboratory types. In addition, the updated material contains: -A new section on design for environmental preservation through the operation and maintenance of health and safety -The latest information on laboratory ventilation and safety systems -Incorporation of "green" laboratory design techniques -Discussions on the architectural, engineering, regulatory, and health and safety aspects unique to the renovation process A wide range of professionals–including those in industrial hygiene, chemical health and safety, laboratory management, and architectural and engineering firms handling laboratory construction and renovation–will find the latest edition of Guidelines for Laboratory Design: Health and Safety Considerations essential reading.

Guidelines for Laboratory Design

Health, Safety, and Environmental Considerations
Author: Louis J. DiBerardinis,Janet S. Baum,Melvin W. First
Publisher: John Wiley & Sons
ISBN: 0470505524
Category: Architecture
Page: 515
View: 6310

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"Focuses on Environmental considerations in addition to health and safety, emphasizing environmental issues in design as well as green lab design. Contains a new section on Sustainable Design. Includes new chapters on Material Sciences and Engineering and Nanotechnology Provides updated information in all sections, especially the chapters on Animal Research and HVAC "--

Laboratory Design, Construction, and Renovation

Participants, Process, and Product
Author: National Research Council,Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Board on Chemical Sciences and Technology,Committee on Design, Construction, and Renovation of Laboratory Facilities
Publisher: National Academies Press
ISBN: 9780309132770
Category: Technology & Engineering
Page: 170
View: 4069

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Laboratory facilities are complex, technically sophisticated, and mechanically intensive structures that are expensive to build and to maintain. Hundreds of decisions must be made before and during new construction or renovation that will determine how successfully the facility will function when completed and how successfully it can be maintained once put into service. This book provides guidance on effective approaches for building laboratory facilities in the chemical and biochemical sciences. It contains both basic and laboratory-specific information addressed to the user community-the scientists and administrators who contract with design and construction experts. The book will also be important to the design and construction communities-the architects, laboratory designers, and engineers who will design the facility and the construction personnel who will build it-to help them communicate with the scientific community for whom they build laboratory facilities.

Design and Planning of Research and Clinical Laboratory Facilities


Author: Leonard Mayer
Publisher: John Wiley & Sons
ISBN: 9780471306238
Category: Architecture
Page: 525
View: 9849

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Laboratory design, a profitable area of specialization for architects, requires an immense knowledge of a maze of codes, regulations, standards and guidelines. Providing a detailed overview of the fundamental building processes, this volume serves as both

Building Type Basics for Research Laboratories


Author: Daniel D. Watch
Publisher: John Wiley & Sons
ISBN: 9780471217572
Category: Architecture
Page: 288
View: 1876

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Planning to initiate designs for government, academic, and private research laboratories? Here's the nuts-and-bolts design guidelines that will start any project off on the right track and keep it there through completion. Filled with project photographs, diagrams, floor plans, sections, and details, Combines in-depth coverage of the structural, mechanical, energy, cost, and safety issues that are unique to research laboratories. Order your copy today!

Sustainable Design of Research Laboratories

Planning, Design, and Operation
Author: KlingStubbins
Publisher: John Wiley & Sons
ISBN: 0470915978
Category: Architecture
Page: 352
View: 3517

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Architecture, Sustainable Design A comprehensive book on the sustainable design of research laboratories Today's research laboratories are complex and difficult building types to design, and making them sustainable adds more obstacles. Written by members of the well-known firm KlingStubbins, under the guidance of its Directors of Laboratory Planning, Engineering, and Sustainability, Sustainable Design of Research Laboratories represents a multidisciplinary approach to addressing these challenges. With the needs of architects, engineers, construction professionals, and facility owners in mind, this book provides a road map for sustainable planning, design, construction, and operations. The book is valuable both to experienced laboratory designers seeking guidance on sustainable strategies, as well as professionals versed in sustainable design who want insight into laboratory applications. With content rich in guidance on performance strategies, even the most technically oriented reader will find valuable lessons inside. This book: Focuses on the links between best sustainable practices and the specific needs of research laboratories Provides a number of case studies of the best contemporary sustainably designed labs, with a focus on architecture and engineering Explores the challenges in applying rating systems, including LEED, to laboratory buildings Examines unique considerations of sustainable approaches in leased and renovated laboratories Includes contributions by experts on approaches to integrated design, site design, programming, and commissioning This important book shows how theoretical ideas can be applied to real-life laboratory projects to create healthier and more efficient research environments.

Planning and Designing Research Animal Facilities


Author: Jack Hessler,Noel Lehner
Publisher: Academic Press
ISBN: 9780080919218
Category: Science
Page: 520
View: 7930

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Research institutions have or are planning to build, expand and renovate animal research facilities to keep up with the demands of biomedical research caused in part by growth in the use of genetically altered rodents and the upsurge of research in infectious diseases. Properly designed facilities greatly facilitate effective management and high-quality day-to-day animal care that is required to optimally support animal research and testing. There are multiple solutions to address the myriad of factors that influence the design and construction of animal research facilities. There is no “best design applicable for all facilities and arguably not even a single “best design for a given facility. For this reason, Planning and Designing Research Animal Facilities is not intended to be a “how to book. The goal is to cover the basic programmatic requirements of animal research facilities, provide ideas for meeting those requirements while, hopefully, stimulating the creative process in which designers in consultation with those who work in animal research facilities generate even better ideas. That is how progress has been made and will continue to be made. Facilitates communication between the parties involved in planning and designing animal facilities by providing contemporary information, and stimulating creativity that will help lead to wise decisions and advance the knowledge base for planning, design and constructing animal research facilities

Chemical Laboratory Safety and Security

A Guide to Developing Standard Operating Procedures
Author: National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Chemical Management Toolkit Expansion: Standard Operating Procedures
Publisher: National Academies Press
ISBN: 0309392209
Category: Science
Page: 116
View: 4249

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The U.S. Department of State charged the Academies with the task of producing a protocol for development of standard operating procedures (SOPs) that would serve as a complement to the Chemical Laboratory Safety and Security: A Guide to Prudent Chemical Management and be included with the other materials in the 2010 toolkit. To accomplish this task, a committee with experience and knowledge in good chemical safety and security practices in academic and industrial laboratories with awareness of international standards and regulations was formed. The hope is that this toolkit expansion product will enhance the use of the previous reference book and the accompanying toolkit, especially in developing countries where safety resources are scarce and experience of operators and end-users may be limited.

Occupational Health and Safety in the Care and Use of Nonhuman Primates


Author: National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Committee on Occupational Health and Safety in the Care and Use of Nonhuman Primates
Publisher: National Academies Press
ISBN: 030908914X
Category: Science
Page: 180
View: 2334

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The field of occupational health and safety constantly changes, especially as it pertains to biomedical research. New infectious hazards are of particular importance at nonhuman-primate facilities. For example, the discovery that B virus can be transmitted via a splash on a mucous membrane raises new concerns that must be addressed, as does the discovery of the Reston strain of Ebola virus in import quarantine facilities in the U.S. The risk of such infectious hazards is best managed through a flexible and comprehensive Occupational Health and Safety Program (OHSP) that can identify and mitigate potential hazards. Occupational Health and Safety in the Care and Use of Nonhuman Primates is intended as a reference for vivarium managers, veterinarians, researchers, safety professionals, and others who are involved in developing or implementing an OHSP that deals with nonhuman primates. The book lists the important features of an OHSP and provides the tools necessary for informed decision-making in developing an optimal program that meets all particular institutional needs.

Laboratories

A Guide to Master Planning, Programming, Procurement, and Design
Author: Fernand Dahan
Publisher: W. W. Norton & Company
ISBN: 9780393730586
Category: Architecture
Page: 298
View: 327

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This comprehensive reference by a senior architect at the EPA covers guidelines for site selection, the design of complete facilities (including sustainable labs) and individual lab rooms, and strategic master planning for architects, engineers, and project managers as well as those who commission, operate, and manage laboratories at every level from schools to industry.

Prudent Practices in the Laboratory:

Handling and Management of Chemical Hazards, Updated Version
Author: The Committee on Prudent Practices in the Laboratory: An Update,Board on Chemical Sciences and Technology,Division on Earth and Life Studies,National Research Council
Publisher: National Academies Press
ISBN: 0309138647
Category: Science
Page: 360
View: 1799

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Prudent Practices in the Laboratory--the book that has served for decades as the standard for chemical laboratory safety practice--now features updates and new topics. This revised edition has an expanded chapter on chemical management and delves into new areas, such as nanotechnology, laboratory security, and emergency planning. Developed by experts from academia and industry, with specialties in such areas as chemical sciences, pollution prevention, and laboratory safety, Prudent Practices in the Laboratory provides guidance on planning procedures for the handling, storage, and disposal of chemicals. The book offers prudent practices designed to promote safety and includes practical information on assessing hazards, managing chemicals, disposing of wastes, and more. Prudent Practices in the Laboratory will continue to serve as the leading source of chemical safety guidelines for people working with laboratory chemicals: research chemists, technicians, safety officers, educators, and students.

Putting Biotechnology to Work:

Bioprocess Engineering
Author: Committee on Bioprocess Engineering,National Research Council,Division on Earth and Life Studies,Commission on Life Sciences
Publisher: National Academies Press
ISBN: 0309047854
Category: Science
Page: 132
View: 8029

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The ability of the United States to sustain a dominant global position in biotechnology lies in maintaining its primacy in basic life-science research and developing a strong resource base for bioprocess engineering and bioproduct manufacturing. This book examines the status of bioprocessing and biotechnology in the United States; current bioprocess technology, products, and opportunities; and challenges of the future and what must be done to meet those challenges. It gives recommendations for action to provide suitable incentives to establish a national program in bioprocess-engineering research, development, education, and technology transfer.

Occupational Health and Safety in the Care and Use of Research Animals


Author: Committee on Occupational Safety and Health in Research Animal Facilities,Institute for Laboratory Animal Research,Commission on Life Sciences,National Research Council
Publisher: National Academies Press
ISBN: 0309052998
Category: Science
Page: 168
View: 9029

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Much has been written about the care of research animals. Yet little guidance has appeared on protecting the health and safety of the people who care for or use these animals. This book, an implementation handbook and companion to Guide For the Care and Use of Laboratory Animals, identifies principles for building a program and discusses the accountability of institutional leaders, managers, and employees for a program's success. It provides a detailed description of risks-- physical and chemical hazards, allergens and zoonoses, and hazards from experiments--which will serve as a continuing reference for the laboratory. The book offers specific recommendations for controlling risk through administrative procedures, facility design, engineering controls, and periodic evaluations. The volume focuses on the worker, with detailed discussions of work practices, the use of personal protective gear, and the development of an emergency response plan. This handbook will be invaluable to administrators, researchers, and employees in any animal research facility. It will also be of interest to personnel in zoos, animal shelters, and veterinary facilities.

Safety and Security Engineering VII


Author: Lombardi, M.
Publisher: WIT Press
ISBN: 1784662119
Category: Architecture
Page: 494
View: 1871

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Papers presented at the 7th in a series of interdisciplinary conferences on safety and security engineering are contained in this book. The papers include the work of engineers, scientists, field researchers, managers and other specialists involved in one or more of the theoretical and practical aspects of safety and security. Safety and Security Engineering, due to its special nature, is an interdisciplinary area of research and application that brings together in a systematic way, many disciplines of engineering, from the traditional to the most technologically advanced. This volume covers topics such as crisis management, security engineering, natural and man-made disasters and emergencies, risk management, and control, protection and mitigation issues. Specific themes include: Risk analysis, assessment and management; System safety engineering; Incident monitoring; Information and communication security; Disaster management; Emergency response; Critical infrastructure protection; Counter terrorism issues; Human factors; Transportation safety and security; Modelling and experiments; Security surveillance systems; Cyber security / E security; Loss prevention; BIM in Safety and Security.

Research Guidelines for Evaluating the Safety and Efficacy of Herbal Medicines


Author: World Health Organization. Regional Office for the Western Pacific
Publisher: World Health Organization
ISBN: 9789290611103
Category: Medical
Page: 86
View: 5205

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Sets out detailed guidelines for conducting scientific research on the safety and efficacy of herbal medicines. The guidelines which reflect the consensus reached by 17 experts in pharmacology biochemistry and traditional medicine respond to the need to assure the safety of widely-used herbal medicines while also facilitating the search for new pharmaceutical products. Specific research criteria are covered together with general principles of investigation including ethical concerns. The book has three parts. The first discusses the special properties of herbal medicines that need to be considered when designing research protocols. The second part provides detailed guidance on the objectives of research the contents of a research protocol and the methods of investigation for non-clinical studies and for Phase I to Phase IV clinical trials. The third part which forms the core of the book presents three sets of research guidelines: for quality specifications of plant materials and preparations for pharmacodynamic and general pharmacological studies of herbal medicines and for toxicity investigation of herbal medicines. Topics covered range from the information required to establish the identity and quality of plant materials or preparations through the selection of appropriate test systems for pharmacodynamic studies to detailed advice on the many different tests examinations observations and experimental procedures required in experimental animals and controls to establish the safety of herbal medicines. The guidelines are intended to facilitate the work of research scientists and clinicians while also furnishing some reference points for the governmental industrial and non-profit organizations providing financial support.

Laboratory Safety for Chemistry Students


Author: Robert H. Hill, Jr.,David C. Finster
Publisher: John Wiley & Sons
ISBN: 1118212649
Category: Science
Page: 552
View: 9613

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"...this substantial and engaging text offers a wealth of practical (in every sense of the word) advice...Every undergraduate laboratory, and, ideally, every undergraduate chemist, should have a copy of what is by some distance the best book I have seen on safety in the undergraduate laboratory." Chemistry World, March 2011 Laboratory Safety for Chemistry Students is uniquely designed to accompany students throughout their four-year undergraduate education and beyond, progressively teaching them the skills and knowledge they need to learn their science and stay safe while working in any lab. This new principles-based approach treats lab safety as a distinct, essential discipline of chemistry, enabling you to instill and sustain a culture of safety among students. As students progress through the text, they’ll learn about laboratory and chemical hazards, about routes of exposure, about ways to manage these hazards, and about handling common laboratory emergencies. Most importantly, they’ll learn that it is very possible to safely use hazardous chemicals in the laboratory by applying safety principles that prevent and minimize exposures. Continuously Reinforces and Builds Safety Knowledge and Safety Culture Each of the book’s eight chapters is organized into three tiers of sections, with a variety of topics suited to beginning, intermediate, and advanced course levels. This enables your students to gather relevant safety information as they advance in their lab work. In some cases, individual topics are presented more than once, progressively building knowledge with new information that’s appropriate at different levels. A Better, Easier Way to Teach and Learn Lab Safety We all know that safety is of the utmost importance; however, instructors continue to struggle with finding ways to incorporate safety into their curricula. Laboratory Safety for Chemistry Students is the ideal solution: Each section can be treated as a pre-lab assignment, enabling you to easily incorporate lab safety into all your lab courses without building in additional teaching time. Sections begin with a preview, a quote, and a brief description of a laboratory incident that illustrates the importance of the topic. References at the end of each section guide your students to the latest print and web resources. Students will also find “Chemical Connections” that illustrate how chemical principles apply to laboratory safety and “Special Topics” that amplify certain sections by exploring additional, relevant safety issues. Visit the companion site at http://userpages.wittenberg.edu/dfinster/LSCS/.

Promoting Chemical Laboratory Safety and Security in Developing Countries


Author: National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Promoting Safe and Secure Chemical Management in Developing Countries
Publisher: National Academies Press
ISBN: 9780309161350
Category: Science
Page: 136
View: 6699

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There is growing concern about the possible use of toxic industrial chemicals or other hazardous chemicals by those seeking to perpetrate acts of terrorism. The U.S. Chemical Security Engagement Program (CSP), funded by the U.S. Department of State and run by Sandia National Laboratories, seeks to develop and facilitate cooperative international activities that promote best practices in chemical security and safe management of toxic chemicals, including: Partnering with host governments, chemical professionals, and industry to assess and fill gaps in chemical security abroad. Providing technical expertise and training to improve best practices in security and safety among chemical professionals and industry. Increasing transparency and accountability for dangerous chemical materials, expertise, and technologies. Providing opportunities for collaboration with the international professional chemical community. The Department of State called on the National Academies to assist in the CSP's efforts to promote chemical safety and security in developing countries.

Laboratory Quality Management System

Handbook
Author: World Health Organization
Publisher: N.A
ISBN: 9789241548274
Category: Medical
Page: 247
View: 9731

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Achieving, maintaining and improving accuracy, timeliness and reliability are major challenges for health laboratories. Countries worldwide committed themselves to build national capacities for the detection of, and response to, public health events of international concern when they decided to engage in the International Health Regulations implementation process. Only sound management of quality in health laboratories will enable countries to produce test results that the international community will trust in cases of international emergency. This handbook was developed through collaboration between the WHO Lyon Office for National Epidemic Preparedness and Response, the United States of America Centers for Disease Control and Prevention (CDC) Division of Laboratory Systems, and the Clinical and Laboratory Standards Institute (CLSI). It is based on training sessions and modules provided by the CDC and WHO in more than 25 countries, and on guidelines for implementation of ISO 15189 in diagnostic laboratories, developed by CLSI. This handbook is intended to provide a comprehensive reference on Laboratory Quality Management System for all stakeholders in health laboratory processes, from management, to administration, to bench-work laboratorians. This handbook covers topics that are essential for quality management of a public health or clinical laboratory. They are based on both ISO 15189 and CLSI GP26-A3 documents. Each topic is discussed in a separate chapter. The chapters follow the framework developed by CLSI and are organized as the "12 Quality System Essentials".

Safe Science

Promoting a Culture of Safety in Academic Chemical Research
Author: Committee on Establishing and Promoting a Culture of Safety in Academic Laboratory Research,National Research Council,Board on Chemical Sciences and Technology,Division on Earth and Life Studies,Board on Human-Systems Integration,Division of Behavioral and Social Sciences and Education
Publisher: National Academy Press
ISBN: 9780309300919
Category: Science
Page: 128
View: 6808

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Recent serious and sometimes fatal accidents in chemical research laboratories at United States universities have driven government agencies, professional societies, industries, and universities themselves to examine the culture of safety in research laboratories. These incidents have triggered a broader discussion of how serious incidents can be prevented in the future and how best to train researchers and emergency personnel to respond appropriately when incidents do occur. As the priority placed on safety increases, many institutions have expressed a desire to go beyond simple compliance with regulations to work toward fostering a strong, positive safety culture: affirming a constant commitment to safety throughout their institutions, while integrating safety as an essential element in the daily work of laboratory researchers. "Safe Science" takes on this challenge. This report examines the culture of safety in research institutions and makes recommendations for university leadership, laboratory researchers, and environmental health and safety professionals to support safety as a core value of their institutions. The report discusses ways to fulfill that commitment through prioritizing funding for safety equipment and training, as well as making safety an ongoing operational priority. A strong, positive safety culture arises not because of a set of rules but because of a constant commitment to safety throughout an organization. Such a culture supports the free exchange of safety information, emphasizes learning and improvement, and assigns greater importance to solving problems than to placing blame. High importance is assigned to safety at all times, not just when it is convenient or does not threaten personal or institutional productivity goals. "Safe Science" will be a guide to make the changes needed at all levels to protect students, researchers, and staff.