Enzyme Kinetics for Systems Biology

Author: Herbert M. Sauro
Publisher: Future Skill Software
ISBN: 0982477317
Category: Science
Page: 308
View: 1226

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The 2nd edition has recently been published, the 1st edition has therefore been reduced in price by 20%. Enzyme Kinetics for System Biology is geared towards those who need a reference or classroom textbook that describes the various rate laws one can use to build computer models of cellular networks. The book covers commonly addressed topics such as rapid-equilibrium and steady state kinetics, including chapters on inhibitors, activators, cooperatively and allostery. The text book also includes topics more relevant to systems biology; these include chapters on elasticities, generalized rate laws and kinetics laws used to describe gene expression. Exercises are provided in most chapters with a summary of all the major kinetic rate laws in an appendix. Chapters include: Reaction Kinetics Elasticities Basic Enzyme Kinetics Enzyme Inhibition and Activation Multireactant Rate Laws Cooperativity Allostery Generalized Rate Laws Kinetics of Gene Regulation Basic Thermodynamics Current Print version: 1.08 Original publication date: April 2011

Enzyme Biocatalysis

Principles and Applications
Author: Andrés Illanes
Publisher: Springer Science & Business Media
ISBN: 1402083610
Category: Technology & Engineering
Page: 392
View: 330

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This book was written with the purpose of providing a sound basis for the design of enzymatic reactions based on kinetic principles, but also to give an updated vision of the potentials and limitations of biocatalysis, especially with respect to recent app- cations in processes of organic synthesis. The ?rst ?ve chapters are structured in the form of a textbook, going from the basic principles of enzyme structure and fu- tion to reactor design for homogeneous systems with soluble enzymes and hete- geneous systems with immobilized enzymes. The last chapter of the book is divided into six sections that represent illustrative case studies of biocatalytic processes of industrial relevance or potential, written by experts in the respective ?elds. We sincerely hope that this book will represent an element in the toolbox of gr- uate students in applied biology and chemical and biochemical engineering and also of undergraduate students with formal training in organic chemistry, biochemistry, thermodynamics and chemical reaction kinetics. Beyond that, the book pretends also to illustrate the potential of biocatalytic processes with case studies in the ?eld of organic synthesis, which we hope will be of interest for the academia and prof- sionals involved in R&D&I. If some of our young readers are encouraged to engage or persevere in their work in biocatalysis this will certainly be our more precious reward.

Kompendium Systembiologie

Mathematische Modellierung und Modellanalyse
Author: Andreas Kremling
Publisher: Springer-Verlag
ISBN: 3834886076
Category: Science
Page: 300
View: 8953

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Das Buch beschreibt die Grundlagen der mathematischen Modellierung zellulärer Systeme. Nach einer Klassifikation von Modellen wird schwerpunktmäßig auf deterministische Modelle eingegangen und für alle relevanten zellulären Prozesse entsprechende Gleichungen angegeben. Anschließend werden eine Reihe von Verfahren zur Modellanalyse vorgestellt. Etwas kürzer werden Verfahren zum Reverse Engineering und zur Analyse von Netzwerkgraphen abgehandelt. Am Ende werden noch Verfahren der Parameteridentifikation besprochen.


The Chemical Reactions of Living Cells
Author: David E. Metzler,Carol M. Metzler
Publisher: Academic Press
ISBN: 9780124925403
Category: Medical
Page: 937
View: 3116

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Biochemistry: The Chemical Reactions of Living Cells is a well-integrated, up-to-date reference for basic biochemistry, associated chemistry, and underlying biological phenomena. Biochemistry is a comprehensive account of the chemical basis of life, describing the amazingly complex structures of the compounds that make up cells, the forces that hold them together, and the chemical reactions that allow for recognition, signaling, and movement. This book contains information on the human body, its genome, and the action of muscles, eyes, and the brain. It also features: thousands of literature references that provide introduction to current research as well as historical background; twice the number of chapters of the first edition; and each chapter contains boxes of information on topics of general interest. -- Publisher description.

RÖMPP Lexikon Biotechnologie und Gentechnik, 2. Auflage, 1999

Author: Monika Deckwer
Publisher: Georg Thieme Verlag
ISBN: 3131795727
Category: Science
Page: 878
View: 9382

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Diese Ausgabe der RÖMPP Chemie-Enzyklopädie von 1999 enthält über 5000 Fachbegriffe rund um Biotechnologie und Gentechnik mit 21.000 Querverweisen, Literaturhinweisen sowie Abbildungen, Formeln und Tabellen. Anwendungsbezogen werden die Stichwörter so leicht verständlich erklärt, dass der RÖMPP auch für Nicht-Chemiker praktisch im Arbeitsalltag einsetzbar ist. Der RÖMPP für Biotechnologie und Gentechnik behandelt in dieser 2. Auflage 31 Fachgebiete von Analytik bis Zellkultur und bietet einen umfassenden Überblick über die folgenden Themen: Grundlagen: Biochemie, Genetik, Fortpflanzungsbiologie, Molekularbiologie, Virologie, Mikrobiologie, Bioanalytik, Zellbiologie. Anwendungen: Gentechnik, Landwirtschaft, Lebensmittel, Pharmazie, Medizin, Immunologie, Verfahrenstechnik, Fermenter, Bioreaktoren, Zellkultur, Umweltbiotechnologie, Biosensoren. Extras: Sicherheit/Arbeitsschutz, Ethik, Gesetzgebung, öffentliche Diskussion, Biotechnologie-Firmen, Fremdwörterlexikon Deutsch-Englisch.

Comprehensive toxicology

Author: I. Glenn Sipes,Charlene A. McQueen,A. Jay Gandolfi
Publisher: N.A
Category: Medical
Page: 498
View: 6495

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Henry's Clinical Diagnosis and Management by Laboratory Methods E-Book

Author: Richard A. McPherson,Matthew R. Pincus
Publisher: Elsevier Health Sciences
ISBN: 1455726842
Category: Medical
Page: 1568
View: 6741

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Recognized as the definitive book in laboratory medicine since 1908, Henry’s Clinical Diagnosis and Management by Laboratory Methods, edited by Richard A. McPherson, MD and Matthew R. Pincus, MD, PhD, is a comprehensive, multidisciplinary pathology reference that gives you state-of-the-art guidance on lab test selection and interpretation of results. Revisions throughout keep you current on the latest topics in the field, such as biochemical markers of bone metabolism, clinical enzymology, pharmacogenomics, and more! A user-friendly full-color layout puts all the latest, most essential knowledge at your fingertips. Update your understanding of the scientific foundation and clinical application of today's complete range of laboratory tests. Get optimal test results with guidance on error detection, correction, and prevention as well as cost-effective test selection. Reference the information you need quickly and easily thanks to a full-color layout, many new color illustrations and visual aids, and an organization by organ system. Master all the latest approaches in clinical laboratory medicine with new and updated coverage of: the chemical basis for analyte assays and common interferences; lipids and dyslipoproteinemia; markers in the blood for cardiac injury evaluation and related stroke disorders; coagulation testing for antiplatelet drugs such as aspirin and clopidogrel; biochemical markers of bone metabolism; clinical enzymology; hematology and transfusion medicine; medical microbiology; body fluid analysis; and many other rapidly evolving frontiers in the field. Effectively monitor the pace of drug clearing in patients undergoing pharmacogenomic treatments with a new chapter on this groundbreaking new area. Apply the latest best practices in clinical laboratory management with special chapters on organization, work flow, quality control, interpretation of results, informatics, financial management, and establishing a molecular diagnostics laboratory. Confidently prepare for the upcoming recertification exams for clinical pathologists set to begin in 2016.

Principles of biochemistry

Author: H. Robert Horton
Publisher: Prentice Hall
ISBN: 9780130424099
Category: Science
Page: 700
View: 9583

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This accurate and up-to-date book focuses on the basic principles of Biochemistry, with carefully selected examples of each. The areas of greatest change since the second edition are lipid metabolism, oxidative phosphorylation, and protein metabolism. Includes stereo views of many macromolecules; computer supplement; a section on molecular evolution; protein structures; molecular evolution; and developments in the area of gene expression, including the structure of RNA polymerase, the structure of the ribosome, genome organization, repair mechanisms, regulation of transcription and translation, and the structure and evolution of aminoacy1-tRNA synthetases. For readers interested in Biochemistry.

Mechanistic Studies of Enolase

An Investigation of the Structure and Function Relationships Among Variant Enolases and the Corresponding Active-site Residues of the Wild-type Enzyme
Author: Paul Abell Sims
Publisher: N.A
Page: 157
View: 3603

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Biochemical systems analysis

a study of function and design in molecular biology
Author: Michael A. Savageau
Publisher: Addison-Wesley
Category: Science
Page: 379
View: 4205

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Chemistry and Biochemistry of Flavoenzymes

Author: Franz Müller
Publisher: CRC Press
ISBN: 9780849343957
Category: Medical
Page: 680
View: 9110

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Chemistry and Biochemistry of Flavoenzymes summarizes the present knowledge of the chemical and physical properties of free flavin, modified flavins occurring in nature, and deazaflavin. This information forms the fundamental basis for understanding the catalytic properties of flavoenzymes. Flavoproteins involved in transport, electron transfer, oxidation, dehydrogenation and hydroxylation reactions are discussed with respect to their biochemical and biophysical properties. The book presents the catalytic mechanisms of the flavoproteins in detail and, where available, three-dimensional structures and molecular biology data are included. The medical aspects of free and protein-bound flavin are also briefly discussed. Chemistry and Biochemistry of Flavoenzymes is an essential reference source for chemists, biochemists, toxicologists, biologists, pharmacologists, and researchers in the pharmaceutical industry.