Biology of Disease


Author: Nessar Ahmed,Maureen Dawson,Chris Smith,Ed Wood
Publisher: Garland Science
ISBN: 1135728712
Category: Science
Page: 600
View: 8064

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Biology of Disease describes the biology of many of the human disorders and disease that are encountered in a clinical setting. It is designed for first and second year students in biomedical science programs and will also be a highly effective reference for health science professionals as well as being valuable to students beginning medical school. Real cases are used to illustrate the importance of biology in understanding the causes of diseases, as well as in diagnosis and therapy.

Biology of Disease Vectors


Author: William H. Marquardt
Publisher: Elsevier
ISBN: 0080494064
Category: Science
Page: 816
View: 6882

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Biology of Disease Vectors presents a comprehensive and advanced discussion of disease vectors and what the future may hold for their control. This edition examines the control of disease vectors through topics such as general biological requirements of vectors, epidemiology, physiology and molecular biology, genetics, principles of control and insecticide resistance. Methods of maintaining vectors in the laboratory are also described in detail. No other single volume includes both basic information on vectors, as well as chapters on cutting-edge topics, authored by the leading experts in the field. The first edition of Biology of Disease Vectors was a landmark text, and this edition promises to have even more impact as a reference for current thought and techniques in vector biology. Current - each chapter represents the present state of knowledge in the subject area Authoritative - authors include leading researchers in the field Complete - provides both independent investigator and the student with a single reference volume which adopts an explicitly evolutionary viewpoint throuoghout all chapters. Useful - conceptual frameworks for all subject areas include crucial information needed for application to difficult problems of controlling vector-borne diseases

Biology of Disease Vectors


Author: William C. Marquardt,Boris C. Kondratieff
Publisher: Elsevier
ISBN: 0124732763
Category: Medical
Page: 785
View: 5831

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Biology of Disease Vectors presents a comprehensive and advanced discussion of disease vectors and what the future may hold for their control. This edition examines the control of disease vectors through topics such as general biological requirements of vectors, epidemiology, physiology and molecular biology, genetics, principles of control and insecticide resistance. Methods of maintaining vectors in the laboratory are also described in detail. No other single volume includes both basic information on vectors, as well as chapters on cutting-edge topics, authored by the leading experts in the field. The first edition of Biology of Disease Vectors was a landmark text, and this edition promises to have even more impact as a reference for current thought and techniques in vector biology. Current - each chapter represents the present state of knowledge in the subject area Authoritative - authors include leading researchers in the field Complete - provides both independent investigator and the student with a single reference volume which adopts an explicitly evolutionary viewpoint throuoghout all chapters. Useful - conceptual frameworks for all subject areas include crucial information needed for application to difficult problems of controlling vector-borne diseases

The Biology of Disease


Author: Jonathan Phillips,Paul G. Murray,Paul Kirk
Publisher: Wiley-Blackwell
ISBN: 9780632054046
Category: Medical
Page: 340
View: 3137

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The second edition of The Biology of Disease is an introductory level text on the biological principles of human disease. The book is aimed at medical students in degree courses in biomedical science. The book fuses the biological (physiological and biochemical) processes which underlie the clinical manifestations of disease. As such, it brings together material which is conventionally dealt with by several books. The authors have covered the fundamentals of each topic in a readable manner, which should encourage students to develop a fuller understanding, where necessary, by reference to more comprehensive texts. Integrates basic science and clinical medicine. Detailed case studies at the end of each chapter which emphasise the clinical setting. New chapters on transplantation immunology, anaemia, toxicology & poisoning. The use of non-technical language for the descriptions in the case studies to ensure that all students will comprehend the underlying principles.

Muscle 2-Volume Set

Fundamental Biology and Mechanisms of Disease
Author: Joseph Hill,Eric Olson
Publisher: Academic Press
ISBN: 0123815118
Category: Science
Page: 1528
View: 4326

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A valuable study of the science behind the medicine, Muscle: Fundamental Biology and Mechanisms of Disease brings together key leaders in muscle biology. These experts provide state-of-the-art insights into the three forms of muscle--cardiac, skeletal, and smooth--from molecular anatomy, basic physiology, disease mechanisms, and targets of therapy. Commonalities and contrasts among these three tissue types are highlighted. This book focuses primarily on the biology of the myocyte. Individuals active in muscle investigation--as well as those new to the field--will find this work useful, as will students of muscle biology. In the case of hte former, many wish to grasp issues at the margins of their own expertise (e.g. clinical matters at one end; molecular matters at the other), adn this book is designed to assist them. Students, postdoctoral fellows, course directors and other faculty will find this book of interest. Beyond this, many clinicians in training (e.g. cardiology fellows) will benefit. The only resource to focus on science before the clinical work and therapeutics Tiered approach to subject: discussion first of normal muscle function through pathological/disease state changes, and ending each section with therapeutic interventions Coverage of topics ranging from basic physiology to newly discovered molecular mechanisms of muscle diseases for all three muscle types: cardiac, skeletal, and smooth

Biology of C Reactive Protein in Health and Disease


Author: Waliza Ansar,Shyamasree Ghosh
Publisher: Springer
ISBN: 8132226801
Category: Medical
Page: 301
View: 2699

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This book offers a comprehensive study of C-reactive protein (CRP) belonging to the pentraxin family, including a brief history of CRP, its structure, synthesis and evolution. Focusing on the emerging role of CRP and its clinical application in the field of disease biology, it details the pathophysiological role of CRP in a host of diseases such as cardiovascular disease, diabetes, cancers, rheumatoid arthritis and infectious diseases and others. It also discusses the role of innate immunity and acute phase response (APR) and their key mediators in the host body in response to tissue injury, infection, trauma or surgery, immunological disorders or neoplastic growth. CRP’s significance in inflammation is highlighted, and its importance as a clinical marker in cardiovascular disease, its functional significance in Leishmania and Plasmodium infections, its association with the development of insulin resistance in type 2 diabetes mellitus, and its role in cancer are discussed in detail. The book also includes clinical data studies and presents the latest research advances to further readers’ understanding of CRP.

Perspectives in Human Malnutrition

A Contribution to the Biology of Disease from a Clinical and Pathological Study of Chronic Malnutrition and Pellagra in the African
Author: Joseph Gillman,Theodor Gillman
Publisher: N.A
ISBN: N.A
Category: Malnutrition
Page: 584
View: 7185

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Molecules, Cells, and Disease

An Introduction to the Biology of Disease
Author: J.L. VanLancker
Publisher: Springer Science & Business Media
ISBN: 146139418X
Category: Medical
Page: 311
View: 543

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In tracing their origin and their fate, the beginning and the end of their environment, humans have often been guided by curiosity. Such concern has helped man to discover, among other things, the structure of the universe from star to atom and the evolution of life from unicellular organism to human being. The study of disease is unique. Although it may have been in spired by the curiosity of a few, it has always been the concern of all, because preventing or curing disease has meant survival not only of individuals, but of entire nations, not only of humans, but of fellow living creatures. If greed, force, religion, and language have been major causes of wars, diseases, more than arms, have often decided the outcome of battles and thereby have woven the pattern of history. For millennia, a large fraction of the human race believed that disease expressed the wrath of God(s) against individuals or societies. Therefore, only priests or priestesses, kings, and queens were endowed with the power of healing. In the West, Hippocrates is credited for exorcising this concept of disease and for objectively describing and cataloguing them. The contributions of Greek physicians to Western medicine made possible more accurate diagnoses and prognoses.

Biology of Bile Acids in Health and Disease


Author: G.P. van Berge Henegouwen,D. Keppler,U. Leuschner,G. Paumgartner,A. Stiehl
Publisher: Springer Science & Business Media
ISBN: 9780792387688
Category: Medical
Page: 336
View: 1581

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Beginning in 1970, the International Bile Acid Meeting has taken place every two years and each time new progress in our understanding of the complex role of bile acids in many metabolic processes of the liver and the intestine has been revealed by a selected group of leading scientists from all over the world. Although originally mainly physiological data on bile acid synthesis and transport were emphasized, and later on also the therapeutic benefit of bile acids in gallstone disease and cholestasis was discovered, we have come now to the molecular biology and genetic era with major discoveries in transport defects and related diseases. This book is the proceedings of Falk Symposium No. 120, held in The Hague, The Netherlands, on October 12-13, 2000 - the 16th International Bile Acid Meeting. One of the main discoveries recently has been the identification of nuclear receptors for bile acids, which gives them a much broader perspective than previously anticipated. It even suggests that bile acids can regulate their biosynthesis and enterohepatic circulation transcriptionally. It will therefore not be surprising that this topic, together with the molecular regulation of cholesterol 7alpha-hydroxylase and cholesterol homeostasis, has a dominant place in these proceedings. Another important topic is the progress in our molecular understanding of hepatic (both at the basolateral and canalicular sites), cholangiocytic and intestinal bile acid transport processes. Further insights into genetic defects causing cholestasis or intestinal malabsorption in animal models and in human diseases are also discussed by a number of well-known authors. Finally the last section deals with new findings on the role of bile acid therapy in cholestatic syndromes or chemoprevention and with the potential benefit of bile acid inhibitors. All contributors provide an update on the most recent developments in their field.

The Liver in Biology and Disease

Liver Biology in Disease, Hepato - Biology in Disease
Author: N.A
Publisher: Elsevier
ISBN: 9780080459264
Category: Science
Page: 600
View: 2834

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The Liver in Biology and Disease was conceived as a sequel in the series Principles of Medical Biology, whose general aim continues to be the integration of human biology and molecular cell biology into modern molecular medicine. It is a volume molded by the Information Revolution which few will deny has forced the teaching faculties in our medical schools to curtail and prune the teaching load and focus on fundamentals and principles. With this intention in mind, a volume of this nature takes into account the close dependence of progress in the medical sciences on bioinformatics (gene and protein analysis) or more precisely, computational biology and of course, the Internet. In general, it follows the pattern of its predecessors. *Chapters are illustrated with numerous figures and references are current *Clear, concise and accurate text about a large number of liver diseases *Describes the liver's histology, biochemistry, and pathology in molecular terms

Molecular Biology of Valvular Heart Disease


Author: Nalini M. Rajamannan
Publisher: Springer Science & Business
ISBN: 1447163508
Category: Medical
Page: 150
View: 8861

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The cellular mechanisms of valvular heart disease have not been elucidated until the last decade. To date, there is no medical therapy that is FDA or CE mark approved for the treatment and/or slowing the progression of this disease. This textbook will provide the cellular basis for medical therapy. Over the past decade, research laboratories are more and more evolving into valvular biology programs from the traditional vascular biology. The science between the two disciplines, although has several similarities has unique cellular targets secondary to the embryologic derivation of the heart valve and the hemodynamics involved in the understanding of this disorders. This textbook will be a natural progression from the recently published text Cardiac Valvular Medicine, Springer 2012. This new textbook will provide the cellular details and the more basic molecular biology approaches towards understanding the disease, providing novel cellular targets and finally developing future clinical trials in the medical treatment of valvular heart disease in the future.

Molecular Biology of Neurodegenerative Diseases


Author: N.A
Publisher: Academic Press
ISBN: 0123858844
Category: Science
Page: 498
View: 6972

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Neurodegenerative diseases result in progressive degeneration and / or death of nerve cells which leads to problems with movement and mental functioning. Examples include Parkinson’s, Alzheimer’s and Huntington’s disease. Much research is taking place to try to identify ways to prevent or lessen the impact of these diseases. This volume reviews the latest research and developments in the molecular biology of neurodegenerative diseases. Contributions from leading authorities Informs and updates on all the latest developments in the field

Macrophages: Biology and Role in the Pathology of Diseases


Author: Subhra K. Biswas,Alberto Mantovani
Publisher: Springer
ISBN: 1493913115
Category: Medical
Page: 615
View: 8203

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Macrophages are a key component of the innate immune system and play an integral role in host defense and homeostasis. On one hand, these cells contribute to host defence by triggering inflammation, displaying microbicidal/tumoricidal properties, regulating the activation of adaptive immunity and promoting resolution of inflammation. On the other hand, they contribute to essential trophic functions such as neural patterning, bone morphogenesis and ductal branching in mammary glands. Thus, macrophages are extremely versatile cells that can respond efficiently to tissue micro environmental cues by polarizing to distinct phenotypes, depending on the functions they need to perform. Indeed, functional diversity and plasticity are hallmarks of these cells. Macrophages may also play a detrimental role. An overwhelming body of literature has indicated their crucial role in pathogenesis. The list includes sepsis, cancer, metabolic syndrome, immunodeficiency, auto-immune disease-virtually impacting every major pathology that we know. These observations have suggested macrophages and their related molecules as potential targets in therapeutic applications. Available evidence proclaims macrophages as a key player in homeostasis, host defense and disease. Crucial developments in the past few years call for a re-evaluation and update of our understanding of macrophages. The present book is an endeavour that attempts provide state-of-the art knowledge of these cells in health and disease.

Systems Biology of Parkinson's Disease


Author: Peter Wellstead,Mathieu Cloutier
Publisher: Springer Science & Business Media
ISBN: 1461434114
Category: Science
Page: 176
View: 3159

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The Systems Biology of Parkinson’s Disease will be underpinned by new measurement techniques. This is particularly true of the pathology of Parkinson's Disease, where recent developments in brain imaging have offered new insights into the morphology of dopaminergic neurons that have profound implications for the special vulnerability and role of this class of neurons.

Biology of Disease


Author: Roz Gibbs,Sheelagh Heugh
Publisher: OUP Oxford
ISBN: 9780199539574
Category: Medical
Page: 368
View: 2290

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Biology of Disease addresses the pathophysiology of specific disease states and evaluates the multidisciplinary approach to disease diagnosis and management. Starting with an introduction to the basic concepts of health and disease, the book graduates to an in-depth discussion of disease states, while illustrating how theory is linked to practice.

Human Biology of Afro-Caribbean Populations


Author: Lorena Madrigal
Publisher: Cambridge University Press
ISBN: 113945353X
Category: Social Science
Page: N.A
View: 3657

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A comprehensive study of the microevolution of Caribbean populations of African descent, this 2006 book reviews the conditions endured by the slaves during their passage and in the plantations and how these conditions may have affected their own health and that of their descendants. Providing an evolutionary framework for understanding the epidemiology of common modern-day diseases such as obesity, hypertension and diabetes, it also looks at infectious diseases and their effect on the genetic make-up of Afro-Caribbean populations. Also covered are population genetics studies that have been used to understand the microevolutionary pathways for various populations, and demographic characteristics including the relationships between migration, family type and fertility. Ending with a case study of the Afro-Caribbean population of Limón, Costa Rica, this book is an essential resource for researchers working in biological anthropology, demography, and epidemiology, and for those interested in the African diaspora in the New World.

Molecular and Cell Biology of Sexually Transmitted Diseases


Author: D.J. Wright,L.C. Archard
Publisher: Springer Science & Business Media
ISBN: 9780412365102
Category: Science
Page: 318
View: 3744

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Molecular and Cell Biology of Human Diseases reviews the status of research on a range of sexually transmitted diseases whose incidence has paralleled the increase in HIV infection and examines the ways in which new methods are influencing current practice and are likely to shape future management.

Dyneins

Structure, Biology and Disease
Author: Stephen M. King
Publisher: Academic Press
ISBN: 0123820057
Category: Science
Page: 656
View: 8540

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Research on dyneins has a direct impact on human diseases, such as viruses and cancer. With an accompanying website showing over 100 streaming videos of cell dynamic behavior for best comprehension of material, Dynein: Structure, Biology and Disease is the only reference covering the structure, biology and application of dynein research to human disease. From bench to bedside, Dynein: Structure, Biology and Disease offers research on fundamental cellular processes to researchers and clinicians across developmental biology, cell biology, molecular biology, biophysics, biomedicine, genetics and medicine. Broad-based up-to-date resource for the dynein class of molecular motors Chapters written by world experts in their topics Numerous well-illustrated figures and tables included to complement the text, imparting comprehensive information on dynein composition, interactions, and other fundamental features

Manual of Biological Markers of Disease


Author: W.J. van Venrooij,Ravinder N. Maini
Publisher: Springer Science & Business Media
ISBN: 9401116709
Category: Medical
Page: 742
View: 5608

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A comprehensive reference work: This looseleaf work is an authoritative compilation of methods for the detection of autoantibodies (Section A: Methods of Autoantibody Detection); the structure, function, and molecular and biochemical concepts of autoantigens (Section B: Autoantigens); and the clinical significance of measuring autoantibodies in patients with rheumatic, connective tissue and autoimmune diseases (Section C: Clinical Significance of Autoantibodies). This unique work brings together all the molecular and medical information - very difficult to retrieve otherwise - in ONE publication. The Editors and contributors are leading experts in the immunological, molecular biological, and clinical fields. The format of this looseleaf publication allows regular updating of data as well as inclusion of new advances in research on autoimmunity. Until now, the work (Basic work including Supplement 1) included Section A, and the larger part of Section B, both in an attractive and robust ringbinder. Audience: By nature and design of this exciting reference work, it is especially aimed at scientists, including immunologists, pathologists and molecular biologists, and clinical chemists, as well as clinicians specializing in rheumatic diseases and autoimmune disorders, inflammation or clinical immunology. Supplement 2: This supplement primarily contains Section C (Clinical Significance of Autoantibodies). As in the other sections, the contents are presented in a consistently structured manner, beautifully illustrated with photos and schematic figures. Extensive literature references are provided. Also, this supplement includes an addition to Section B (Autoantigens), being chapter B.1.5: The Antigens Defined by Antikeratin Antibodies (AKA).